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Five birds, one stone: neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody.
Rouha H, Badarau A, Visram ZC, Battles MB, Prinz B, Magyarics Z, Nagy G, Mirkina I, Stulik L, Zerbs M, Jägerhofer M, Maierhofer B, Teubenbacher A, Dolezilkova I, Gross K, Banerjee S, Zauner G, Malafa S, Zmajkovic J, Maier S, Mabry R, Krauland E, Wittrup KD, Gerngross TU, Nagy E. Rouha H, et al. Among authors: nagy g, nagy e. MAbs. 2015;7(1):243-54. doi: 10.4161/19420862.2014.985132. MAbs. 2015. PMID: 25523282 Free PMC article.
Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies.
Badarau A, Rouha H, Malafa S, Battles MB, Walker L, Nielson N, Dolezilkova I, Teubenbacher A, Banerjee S, Maierhofer B, Weber S, Stulik L, Logan DT, Welin M, Mirkina I, Pleban C, Zauner G, Gross K, Jägerhofer M, Magyarics Z, Nagy E. Badarau A, et al. Among authors: nagy e. MAbs. 2016 Oct;8(7):1347-1360. doi: 10.1080/19420862.2016.1215791. Epub 2016 Jul 28. MAbs. 2016. PMID: 27467113 Free PMC article.
Improved Protection in a Rabbit Model of Community-Associated Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia upon Neutralization of Leukocidins in Addition to Alpha-Hemolysin.
Diep BA, Le VT, Visram ZC, Rouha H, Stulik L, Dip EC, Nagy G, Nagy E. Diep BA, et al. Among authors: nagy g, nagy e. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6333-40. doi: 10.1128/AAC.01213-16. Print 2016 Oct. Antimicrob Agents Chemother. 2016. PMID: 27527081 Free PMC article.
Preventing lung pathology and mortality in rabbit Staphylococcus aureus pneumonia models with cytotoxin-neutralizing monoclonal IgGs penetrating the epithelial lining fluid.
Stulik L, Rouha H, Labrousse D, Visram ZC, Badarau A, Maierhofer B, Groß K, Weber S, Kramarić MD, Glojnarić I, Nagy G, Croisier D, Nagy E. Stulik L, et al. Among authors: nagy g, nagy e. Sci Rep. 2019 Mar 29;9(1):5339. doi: 10.1038/s41598-019-41826-6. Sci Rep. 2019. PMID: 30926865 Free PMC article.
1,906 results