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The dependence of viral RNA replication on co-opted host factors.
Nagy PD, Pogany J. Nagy PD, et al. Nat Rev Microbiol. 2011 Dec 19;10(2):137-49. doi: 10.1038/nrmicro2692. Nat Rev Microbiol. 2011. PMID: 22183253 Free PMC article. Review.
Partial purification and characterization of Cucumber necrosis virus and Tomato bushy stunt virus RNA-dependent RNA polymerases: similarities and differences in template usage between tombusvirus and carmovirus RNA-dependent RNA polymerases.
Nagy PD, Pogany J. Nagy PD, et al. Virology. 2000 Oct 25;276(2):279-88. doi: 10.1006/viro.2000.0577. Virology. 2000. PMID: 11040120
Reduced generation of a 3'-terminal extension product in the preceding assay suggests that the previously characterized replication enhancer present in sat-RNA C (Nagy et al., 1999, EMBO J. 18, 5653-5665) does not stimulate tombusvirus RdRp activity. ...
Reduced generation of a 3'-terminal extension product in the preceding assay suggests that the previously characterized replication enhancer …
In vivo and in vitro characterization of an RNA replication enhancer in a satellite RNA associated with turnip crinkle virus.
Nagy PD, Pogany J, Simon AE. Nagy PD, et al. Virology. 2001 Sep 30;288(2):315-24. doi: 10.1006/viro.2001.1099. Virology. 2001. PMID: 11601903
Nagy, J. Pogany, and A. E. Simon, EMBO J. 1999, 18, 5653-5665). We have found that replacement of 28 nt of the satC enhancer, termed the motif1-hairpin, with 28 randomized bases reduced satC accumulation 8- to 13-fold in Arabidopsis thaliana protoplasts. ...
Nagy, J. Pogany, and A. E. Simon, EMBO J. 1999, 18, 5653-5665). We have found that replacement of 28 nt of the satC enhancer, termed
Internal initiation by the cucumber necrosis virus RNA-dependent RNA polymerase is facilitated by promoter-like sequences.
Panavas T, Pogany J, Nagy PD. Panavas T, et al. Virology. 2002 May 10;296(2):275-87. doi: 10.1006/viro.2002.1422. Virology. 2002. PMID: 12069526
An unusual feature of the tombusvirus RdRp that is partially purified from cucumber necrosis virus (CNV)-infected plants is the ability to initiate complementary RNA synthesis from several internal positions on minus-strand templates derived from DI RNAs ( Nagy and Pogany, …
An unusual feature of the tombusvirus RdRp that is partially purified from cucumber necrosis virus (CNV)-infected plants is the ability to i …
The RNA replication enhancer element of tombusviruses contains two interchangeable hairpins that are functional during plus-strand synthesis.
Panavas T, Nagy PD. Panavas T, et al. J Virol. 2003 Jan;77(1):258-69. doi: 10.1128/jvi.77.1.258-269.2003. J Virol. 2003. PMID: 12477831 Free PMC article.
Nagy and J. Pogany, Virology 276:279-288, 2000), we demonstrate that the minus-strand templates of tombusviruses contain a replication enhancer, which can upregulate RNA synthesis initiating from the minimal plus-strand initiation promoter by 10- to 20-fold in an in vitro
Nagy and J. Pogany, Virology 276:279-288, 2000), we demonstrate that the minus-strand templates of tombusviruses contain a replicatio
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