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RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes.
Heib T, Hermanns HM, Manukjan G, Englert M, Kusch C, Becker IC, Gerber A, Wackerbarth LM, Burkard P, Dandekar T, Balkenhol J, Jahn D, Beck S, Meub M, Dütting S, Stigloher C, Sauer M, Cherpokova D, Schulze H, Brakebusch C, Nieswandt B, Nagy Z, Pleines I. Heib T, et al. Among authors: nagy z. Cell Rep. 2021 May 11;35(6):109102. doi: 10.1016/j.celrep.2021.109102. Cell Rep. 2021. PMID: 33979620 Free article.
CLP36 is a negative regulator of glycoprotein VI signaling in platelets.
Gupta S, Braun A, Morowski M, Premsler T, Bender M, Nagy Z, Sickmann A, Hermanns HM, Bösl M, Nieswandt B. Gupta S, et al. Among authors: nagy z. Circ Res. 2012 Nov 9;111(11):1410-20. doi: 10.1161/CIRCRESAHA.112.264754. Epub 2012 Sep 5. Circ Res. 2012. PMID: 22955732
Actin/microtubule crosstalk during platelet biogenesis in mice is critically regulated by Twinfilin1 and Cofilin1.
Becker IC, Scheller I, Wackerbarth LM, Beck S, Heib T, Aurbach K, Manukjan G, Gross C, Spindler M, Nagy Z, Witke W, Lappalainen P, Bender M, Schulze H, Pleines I, Nieswandt B. Becker IC, et al. Among authors: nagy z. Blood Adv. 2020 May 26;4(10):2124-2134. doi: 10.1182/bloodadvances.2019001303. Blood Adv. 2020. PMID: 32407474 Free PMC article.
G6b-B regulates an essential step in megakaryocyte maturation.
Becker IC, Nagy Z, Manukjan G, Haffner-Luntzer M, Englert M, Heib T, Vögtle T, Gross C, Bharti R, Dietrich S, Mott K, Heck J, Stegmaier S, Baranowsky A, Schinke T, Schlegel N, Heckel T, Stegner D, Pleines I, Ignatius A, Schulze H, Nieswandt B. Becker IC, et al. Among authors: nagy z. Blood Adv. 2022 May 24;6(10):3155-3161. doi: 10.1182/bloodadvances.2021006151. Blood Adv. 2022. PMID: 35134123 Free PMC article.
Impaired microtubule dynamics contribute to microthrombocytopenia in RhoB-deficient mice.
Englert M, Aurbach K, Becker IC, Gerber A, Heib T, Wackerbarth LM, Kusch C, Mott K, Araujo GHM, Baig AA, Dütting S, Knaus UG, Stigloher C, Schulze H, Nieswandt B, Pleines I, Nagy Z. Englert M, et al. Among authors: nagy z. Blood Adv. 2022 Sep 13;6(17):5184-5197. doi: 10.1182/bloodadvances.2021006545. Blood Adv. 2022. PMID: 35819450 Free PMC article.
PDE5A: Key Enzyme to Overcome Platelet Inhibition.
Nagy Z, Nieswandt B. Nagy Z, et al. Thromb Haemost. 2023 Feb;123(2):131-132. doi: 10.1055/a-2000-8406. Epub 2022 Dec 19. Thromb Haemost. 2023. PMID: 36535656 No abstract available.
Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B.
Vögtle T, Sharma S, Mori J, Nagy Z, Semeniak D, Scandola C, Geer MJ, Smith CW, Lane J, Pollack S, Lassila R, Jouppila A, Barr AJ, Ogg DJ, Howard TD, McMiken HJ, Warwicker J, Geh C, Rowlinson R, Abbott WM, Eckly A, Schulze H, Wright GJ, Mazharian A, Fütterer K, Rajesh S, Douglas MR, Senis YA. Vögtle T, et al. Among authors: nagy z. Elife. 2019 Aug 22;8:e46840. doi: 10.7554/eLife.46840. Elife. 2019. PMID: 31436532 Free PMC article.
Lymphatic blood filling in CLEC-2-deficient mouse models.
Haining EJ, Lowe KL, Wichaiyo S, Kataru RP, Nagy Z, Kavanagh DP, Lax S, Di Y, Nieswandt B, Ho-Tin-Noé B, Mehrara BJ, Senis YA, Rayes J, Watson SP. Haining EJ, et al. Among authors: nagy z. Platelets. 2021 Apr 3;32(3):352-367. doi: 10.1080/09537104.2020.1734784. Epub 2020 Mar 4. Platelets. 2021. PMID: 32129691 Free PMC article.
1,835 results