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Differential reaction kinetics, cleavage complex formation, and nonamer binding domain dependence dictate the structure-specific and sequence-specific nuclease activity of RAGs.
Naik AK, Raghavan SC. Naik AK, et al. J Mol Biol. 2012 Jan 20;415(3):475-88. doi: 10.1016/j.jmb.2011.11.002. Epub 2011 Nov 12. J Mol Biol. 2012. PMID: 22119487
P1 nuclease cleavage is dependent on length of the mismatches in DNA.
Naik AK, Raghavan SC. Naik AK, et al. DNA Repair (Amst). 2008 Aug 2;7(8):1384-91. doi: 10.1016/j.dnarep.2008.04.010. Epub 2008 Jun 4. DNA Repair (Amst). 2008. PMID: 18524693
Cytosines, but not purines, determine recombination activating gene (RAG)-induced breaks on heteroduplex DNA structures: implications for genomic instability.
Naik AK, Lieber MR, Raghavan SC. Naik AK, et al. J Biol Chem. 2010 Mar 5;285(10):7587-97. doi: 10.1074/jbc.M109.089631. Epub 2010 Jan 5. J Biol Chem. 2010. PMID: 20051517 Free PMC article.
An anti-silencer- and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development.
Hao B, Naik AK, Watanabe A, Tanaka H, Chen L, Richards HW, Kondo M, Taniuchi I, Kohwi Y, Kohwi-Shigematsu T, Krangel MS. Hao B, et al. J Exp Med. 2015 May 4;212(5):809-24. doi: 10.1084/jem.20142207. Epub 2015 Apr 6. J Exp Med. 2015. PMID: 25847946 Free PMC article.
Specification of Vδ and Vα usage by Tcra/Tcrd locus V gene segment promoters.
Naik AK, Hawwari A, Krangel MS. Naik AK, et al. J Immunol. 2015 Jan 15;194(2):790-4. doi: 10.4049/jimmunol.1402423. Epub 2014 Dec 3. J Immunol. 2015. PMID: 25472997 Free PMC article.
A role of the CTCF binding site at enhancer Eα in the dynamic chromatin organization of the Tcra-Tcrd locus.
Zhao H, Li Z, Zhu Y, Bian S, Zhang Y, Qin L, Naik AK, He J, Zhang Z, Krangel MS, Hao B. Zhao H, et al. Among authors: naik ak. Nucleic Acids Res. 2020 Aug 27:gkaa711. doi: 10.1093/nar/gkaa711. Online ahead of print. Nucleic Acids Res. 2020. PMID: 32853367
Analysis of modified double-bundle anterior cruciate ligament reconstruction with implantless fixation on tibial side.
Sinha S, Naik AK, Kumar A, Jacob T, Kar S. Sinha S, et al. Among authors: naik ak. Chin J Traumatol. 2020 Apr 30:S1008-1275(20)30114-0. doi: 10.1016/j.cjtee.2020.04.007. Online ahead of print. Chin J Traumatol. 2020. PMID: 32417042 Free article.
Enhanced all-optical cavity-tuning using graphene.
Dash A, Palanchoke U, Gely M, Jourdan G, Hentz S, Selvaraja SK, Naik AK. Dash A, et al. Among authors: naik ak. Opt Express. 2019 Nov 11;27(23):34093-34102. doi: 10.1364/OE.27.034093. Opt Express. 2019. PMID: 31878465
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