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Emerging roles for modulation of microRNA signatures in cancer chemoprevention.
Neelakandan K, Babu P, Nair S. Neelakandan K, et al. Curr Cancer Drug Targets. 2012 Jul;12(6):716-40. doi: 10.2174/156800912801784875. Curr Cancer Drug Targets. 2012. PMID: 22515522 Review.
This review focuses on the putative role(s) of miRNAs in different aspects of tumorigenesis and at various stages of early drug discovery that makes them a promising class of drug targets for chemopreventive intervention in cancer. ...Taken together, a better understanding …
This review focuses on the putative role(s) of miRNAs in different aspects of tumorigenesis and at various stages of early drug disco …
Saffron chemoprevention in biology and medicine: a review.
Nair SC, Kurumboor SK, Hasegawa JH. Nair SC, et al. Cancer Biother. 1995 Winter;10(4):257-64. doi: 10.1089/cbr.1995.10.257. Cancer Biother. 1995. PMID: 8590890 Review.
Antitumour principles from Ixora javanica.
Nair SC, Panikkar KR. Nair SC, et al. Cancer Lett. 1990 Feb;49(2):121-6. doi: 10.1016/0304-3835(90)90147-p. Cancer Lett. 1990. PMID: 2306704
In vitro cytotoxic studies showed 50% cytotoxicity to Dalton's lymphoma (DLA) and Ehrlich Ascites tumour cells at a concentration of 12 micrograms and 65 micrograms, respectively, with no activity against normal lymphocytes but preferential activity for lymphocytes derived …
In vitro cytotoxic studies showed 50% cytotoxicity to Dalton's lymphoma (DLA) and Ehrlich Ascites tumour cells at a concentration of …
Antitumour activity of saffron (Crocus sativus).
Nair SC, Pannikar B, Panikkar KR. Nair SC, et al. Cancer Lett. 1991 May 1;57(2):109-14. doi: 10.1016/0304-3835(91)90203-t. Cancer Lett. 1991. PMID: 2025883
Antitumor activity of saffron (Crocus sativus) extract a commonly used spice in India was studied against intraperitoneally transplanted sarcoma-180 (S-180), Ehrlich ascites Carcinoma (EAC) and Dalton's lymphoma ascites (DLA) tumours in mice. Oral administration of …
Antitumor activity of saffron (Crocus sativus) extract a commonly used spice in India was studied against intraperitoneally transplanted sar …
Emerging roles for clinical pharmacometrics in cancer precision medicine.
Nair S, Kong AT. Nair S, et al. Curr Pharmacol Rep. 2018 Jun;4(3):276-283. doi: 10.1007/s40495-018-0139-0. Epub 2018 Apr 20. Curr Pharmacol Rep. 2018. PMID: 30345221 Free PMC article.
In medical oncology, where immediate patient care is the clinician's primary concern, pharmacometric approaches can be tailored to build models that rely on patient data already digitally available in the Electronic Health Record (EHR) to facilitate quick collaboration and …
In medical oncology, where immediate patient care is the clinician's primary concern, pharmacometric approaches can be tailored to bu …
Antitumour principles from Nigella sativa seeds.
Salomi NJ, Nair SC, Jayawardhanan KK, Varghese CD, Panikkar KR. Salomi NJ, et al. Cancer Lett. 1992 Mar 31;63(1):41-6. doi: 10.1016/0304-3835(92)90087-c. Cancer Lett. 1992. PMID: 1555206
The active principle of Nigella sativa seeds containing certain fatty acids was studied for antitumour activities against Ehrlich ascites carcinoma (EAC), Dalton's lymphonia ascites (DLA) and Sarcoma-180 (S-180) cells. In vitro cytotoxic studies showed 50% cytotoxic …
The active principle of Nigella sativa seeds containing certain fatty acids was studied for antitumour activities against Ehrlich ascites ca …
Diet intervention for modifying cancer risk.
Birt DF, Pelling JC, Nair S, Lepley D. Birt DF, et al. Prog Clin Biol Res. 1996;395:223-34. Prog Clin Biol Res. 1996. PMID: 8895992 Review.
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