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Modulating TRADD to restore cellular homeostasis and inhibit apoptosis.
Xu D, Zhao H, Jin M, Zhu H, Shan B, Geng J, Dziedzic SA, Amin P, Mifflin L, Naito MG, Najafov A, Xing J, Yan L, Liu J, Qin Y, Hu X, Wang H, Zhang M, Manuel VJ, Tan L, He Z, Sun ZJ, Lee VMY, Wagner G, Yuan J. Xu D, et al. Among authors: naito mg. Nature. 2020 Nov;587(7832):133-138. doi: 10.1038/s41586-020-2757-z. Epub 2020 Sep 23. Nature. 2020. PMID: 32968279
TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging.
Xu D, Jin T, Zhu H, Chen H, Ofengeim D, Zou C, Mifflin L, Pan L, Amin P, Li W, Shan B, Naito MG, Meng H, Li Y, Pan H, Aron L, Adiconis X, Levin JZ, Yankner BA, Yuan J. Xu D, et al. Among authors: naito mg. Cell. 2018 Sep 6;174(6):1477-1491.e19. doi: 10.1016/j.cell.2018.07.041. Epub 2018 Aug 23. Cell. 2018. PMID: 30146158 Free PMC article.
Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response.
Li W, Shan B, Zou C, Wang H, Zhang MM, Zhu H, Naito MG, Xu D, Manuel VJ, Mifflin L, Hou Z, Ravits J, Yuan J. Li W, et al. Among authors: naito mg. Cell Res. 2022 Jul;32(7):621-637. doi: 10.1038/s41422-022-00673-3. Epub 2022 Jun 3. Cell Res. 2022. PMID: 35661830 Free PMC article.