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Targeted demethylation at the CDKN1C/p57 locus induces human β cell replication.
Ou K, Yu M, Moss NG, Wang YJ, Wang AW, Nguyen SC, Jiang C, Feleke E, Kameswaran V, Joyce EF, Naji A, Glaser B, Avrahami D, Kaestner KH. Ou K, et al. Among authors: naji a. J Clin Invest. 2019 Jan 2;129(1):209-214. doi: 10.1172/JCI99170. Epub 2018 Nov 26. J Clin Invest. 2019. PMID: 30352048 Free PMC article.
Epigenomic plasticity enables human pancreatic α to β cell reprogramming.
Bramswig NC, Everett LJ, Schug J, Dorrell C, Liu C, Luo Y, Streeter PR, Naji A, Grompe M, Kaestner KH. Bramswig NC, et al. Among authors: naji a. J Clin Invest. 2013 Mar;123(3):1275-84. doi: 10.1172/JCI66514. Epub 2013 Feb 22. J Clin Invest. 2013. PMID: 23434589 Free PMC article.
LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.
Ediger BN, Lim HW, Juliana C, Groff DN, Williams LT, Dominguez G, Liu JH, Taylor BL, Walp ER, Kameswaran V, Yang J, Liu C, Hunter CS, Kaestner KH, Naji A, Li C, Sander M, Stein R, Sussel L, Won KJ, May CL, Stoffers DA. Ediger BN, et al. Among authors: naji a. J Clin Invest. 2017 Jan 3;127(1):215-229. doi: 10.1172/JCI88016. Epub 2016 Dec 12. J Clin Invest. 2017. PMID: 27941246 Free PMC article.
Single-Cell Transcriptomics of the Human Endocrine Pancreas.
Wang YJ, Schug J, Won KJ, Liu C, Naji A, Avrahami D, Golson ML, Kaestner KH. Wang YJ, et al. Among authors: naji a. Diabetes. 2016 Oct;65(10):3028-38. doi: 10.2337/db16-0405. Epub 2016 Jun 30. Diabetes. 2016. PMID: 27364731 Free PMC article.
α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody-positive individuals.
Doliba NM, Rozo AV, Roman J, Qin W, Traum D, Gao L, Liu J, Manduchi E, Liu C, Golson ML, Vahedi G, Naji A, Matschinsky FM, Atkinson MA, Powers AC, Brissova M, Kaestner KH, Stoffers DA; HPAP Consortium. Doliba NM, et al. Among authors: naji a. J Clin Invest. 2022 Jun 1;132(11):e156243. doi: 10.1172/JCI156243. J Clin Invest. 2022. PMID: 35642629 Free PMC article.
Functional and Metabolomic Consequences of KATP Channel Inactivation in Human Islets.
Li C, Ackermann AM, Boodhansingh KE, Bhatti TR, Liu C, Schug J, Doliba N, Han B, Cosgrove KE, Banerjee I, Matschinsky FM, Nissim I, Kaestner KH, Naji A, Adzick NS, Dunne MJ, Stanley CA, De León DD. Li C, et al. Among authors: naji a. Diabetes. 2017 Jul;66(7):1901-1913. doi: 10.2337/db17-0029. Epub 2017 Apr 25. Diabetes. 2017. PMID: 28442472 Free PMC article.
612 results