Secondary-site mutation restores the transport defect caused by the transmembrane domain mutation of the xenobiotic transporter MexB in Pseudomonas aeruginosa.
Yoneyama H, Maseda H, Yamabayashi Ta TA, Izumi S, Nakae T.
Yoneyama H, et al. Among authors: nakae t.
Biochem Biophys Res Commun. 2002 Mar 29;292(2):513-8. doi: 10.1006/bbrc.2002.6659.
Biochem Biophys Res Commun. 2002.
PMID: 11906191
This result provided strong support for the recent notion that negatively charged residues in TMS-4 might form a salt-bridge with a positive charge in TMS-10 (Guan, L., and Nakae, T. (2001) J. Bacteriol. 183, 1734-1739). The transporter function impaired by the Gly3 …
This result provided strong support for the recent notion that negatively charged residues in TMS-4 might form a salt-bridge with a positive …