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Sphingosine kinase 1 expression is downregulated during differentiation of Friend cells due to decreased c-MYB.
Mizutani N, Kobayashi M, Sobue S, Ichihara M, Ito H, Tanaka K, Iwaki S, Fujii S, Ito Y, Tamiya-Koizumi K, Takagi A, Kojima T, Naoe T, Suzuki M, Nakamura M, Banno Y, Nozawa Y, Murate T. Mizutani N, et al. Among authors: nakamura m. Biochim Biophys Acta. 2013 May;1833(5):1006-16. doi: 10.1016/j.bbamcr.2013.01.001. Epub 2013 Jan 14. Biochim Biophys Acta. 2013. PMID: 23328083
Down regulation of a harmful variant protein by replacement of its normal protein.
Ando Y, Yamashita T, Nakamura M, Tanaka Y, Hashimoto M, Tashima K, Suhr O, Uemura Y, Obayashi K, Terazaki H, Suga M, Uchino M, Ando M. Ando Y, et al. Among authors: nakamura m. Biochim Biophys Acta. 1997 Nov 28;1362(1):39-46. doi: 10.1016/s0925-4439(97)00054-9. Biochim Biophys Acta. 1997. PMID: 9434098 Clinical Trial.
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