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The hyperglycemia stimulated myocardial endoplasmic reticulum (ER) stress contributes to diabetic cardiomyopathy in the transgenic non-obese type 2 diabetic rats: a differential role of unfolded protein response (UPR) signaling proteins.
Lakshmanan AP, Harima M, Suzuki K, Soetikno V, Nagata M, Nakamura T, Takahashi T, Sone H, Kawachi H, Watanabe K. Lakshmanan AP, et al. Among authors: nakamura t. Int J Biochem Cell Biol. 2013 Feb;45(2):438-47. doi: 10.1016/j.biocel.2012.09.017. Epub 2012 Sep 29. Int J Biochem Cell Biol. 2013. PMID: 23032698
Beneficial effects of edaravone, a novel antioxidant, in rats with dilated cardiomyopathy.
Arumugam S, Thandavarayan RA, Veeraveedu PT, Nakamura T, Arozal W, Sari FR, Giridharan VV, Soetikno V, Palaniyandi SS, Harima M, Suzuki K, Nagata M, Kodama M, Watanabe K. Arumugam S, et al. Among authors: nakamura t. J Cell Mol Med. 2012 Sep;16(9):2176-85. doi: 10.1111/j.1582-4934.2012.01526.x. J Cell Mol Med. 2012. PMID: 22268705 Free PMC article.
Telmisartan treatment targets inflammatory cytokines to suppress the pathogenesis of acute colitis induced by dextran sulphate sodium.
Arumugam S, Sreedhar R, Thandavarayan RA, Giridharan VV, Karuppagounder V, Pitchaimani V, Afrin MR, Miyashita S, Nomoto M, Harima M, Suzuki H, Nakamura T, Nakamura M, Suzuki K, Watanabe K. Arumugam S, et al. Among authors: nakamura m, nakamura t. Cytokine. 2015 Aug;74(2):305-12. doi: 10.1016/j.cyto.2015.03.017. Epub 2015 Apr 11. Cytokine. 2015. PMID: 25873126
Pruni cortex ameliorates skin inflammation possibly through HMGB1-NFκB pathway in house dust mite induced atopic dermatitis NC/Nga transgenic mice.
Watanabe K, Karuppagounder V, Arumugam S, Thandavarayan RA, Pitchaimani V, Sreedhar R, Afrin R, Harima M, Suzuki H, Suzuki K, Nakamura T, Nomoto M, Miyashita S, Fukumoto K, Ueno K. Watanabe K, et al. Among authors: nakamura t. J Clin Biochem Nutr. 2015 May;56(3):186-94. doi: 10.3164/jcbn.14-75. Epub 2015 Jan 28. J Clin Biochem Nutr. 2015. PMID: 26060348 Free PMC article.
Toki-shakuyaku-san, a Japanese kampo medicine, reduces colon inflammation in a mouse model of acute colitis.
Sreedhar R, Arumugam S, Thandavarayan RA, Giridharan VV, Karuppagounder V, Pitchaimani V, Afrin R, Harima M, Nakamura T, Ueno K, Nakamura M, Suzuki K, Watanabe K. Sreedhar R, et al. Among authors: nakamura m, nakamura t. Int Immunopharmacol. 2015 Dec;29(2):869-875. doi: 10.1016/j.intimp.2015.08.029. Epub 2015 Sep 4. Int Immunopharmacol. 2015. PMID: 26344429
Jumihaidokuto effectively inhibits colon inflammation and apoptosis in mice with acute colitis.
Sreedhar R, Arumugam S, Karuppagounder V, Thandavarayan RA, Giridharan VV, Pitchaimani V, Afrin MR, Harima M, Nakamura T, Nakamura M, Suzuki K, Watanabe K. Sreedhar R, et al. Among authors: nakamura m, nakamura t. Int Immunopharmacol. 2015 Dec;29(2):957-963. doi: 10.1016/j.intimp.2015.10.009. Epub 2015 Nov 6. Int Immunopharmacol. 2015. PMID: 26548346
Fasting time duration modulates the onset of insulin-induced hypoglycemic seizures in mice.
Pitchaimani V, Arumugam S, Thandavarayan RA, Karuppagounder V, Afrin MR, Sreedhar R, Harima M, Suzuki H, Miyashita S, Nakamura T, Suzuki K, Nakamura M, Ueno K, Watanabe K. Pitchaimani V, et al. Among authors: nakamura m, nakamura t. Epilepsy Res. 2016 Sep;125:47-51. doi: 10.1016/j.eplepsyres.2016.06.009. Epub 2016 Jun 26. Epilepsy Res. 2016. PMID: 27392286
Le Carbone, a charcoal supplement, modulates DSS-induced acute colitis in mice through activation of AMPKα and downregulation of STAT3 and caspase 3 dependent apoptotic pathways.
Afrin MR, Arumugam S, Rahman MA, Karuppagounder V, Sreedhar R, Harima M, Suzuki H, Nakamura T, Miyashita S, Suzuki K, Ueno K, Watanabe K. Afrin MR, et al. Among authors: nakamura t. Int Immunopharmacol. 2017 Feb;43:70-78. doi: 10.1016/j.intimp.2016.10.023. Epub 2016 Dec 12. Int Immunopharmacol. 2017. PMID: 27978459
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