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A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway.
Morimitsu Y, Nakagawa Y, Hayashi K, Fujii H, Kumagai T, Nakamura Y, Osawa T, Horio F, Itoh K, Iida K, Yamamoto M, Uchida K. Morimitsu Y, et al. Among authors: nakamura y. J Biol Chem. 2002 Feb 1;277(5):3456-63. doi: 10.1074/jbc.M110244200. Epub 2001 Nov 12. J Biol Chem. 2002. PMID: 11706044 Free article.
We have recently developed a cell culture system, using rat liver epithelial RL 34 cells, that potently responds to the phenolic antioxidants resulting in the induction of GST activity (Kawamoto, Y., Nakamura, Y., Naito, Y., Torii, Y., Kumagai, …
We have recently developed a cell culture system, using rat liver epithelial RL 34 cells, that potently responds to the phenolic antioxidant …
Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation accompanied by apoptosis: the alpha,beta-unsaturated carbonyl group is a prerequisite.
Murakami A, Takahashi D, Kinoshita T, Koshimizu K, Kim HW, Yoshihiro A, Nakamura Y, Jiwajinda S, Terao J, Ohigashi H. Murakami A, et al. Among authors: nakamura y. Carcinogenesis. 2002 May;23(5):795-802. doi: 10.1093/carcin/23.5.795. Carcinogenesis. 2002. PMID: 12016152
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