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c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis.
Piao X, Komazawa-Sakon S, Nishina T, Koike M, Piao JH, Ehlken H, Kurihara H, Hara M, Van Rooijen N, Schütz G, Ohmuraya M, Uchiyama Y, Yagita H, Okumura K, He YW, Nakano H. Piao X, et al. Among authors: nakano h. Sci Signal. 2012 Dec 18;5(255):ra93. doi: 10.1126/scisignal.2003558. Sci Signal. 2012. PMID: 23250397 Free PMC article.
Importin β1 protein-mediated nuclear localization of death receptor 5 (DR5) limits DR5/tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced cell death of human tumor cells.
Kojima Y, Nakayama M, Nishina T, Nakano H, Koyanagi M, Takeda K, Okumura K, Yagita H. Kojima Y, et al. Among authors: nakano h. J Biol Chem. 2011 Dec 16;286(50):43383-93. doi: 10.1074/jbc.M111.309377. Epub 2011 Oct 21. J Biol Chem. 2011. PMID: 22020938 Free PMC article.
Crucial role for autophagy in degranulation of mast cells.
Ushio H, Ueno T, Kojima Y, Komatsu M, Tanaka S, Yamamoto A, Ichimura Y, Ezaki J, Nishida K, Komazawa-Sakon S, Niyonsaba F, Ishii T, Yanagawa T, Kominami E, Ogawa H, Okumura K, Nakano H. Ushio H, et al. Among authors: nakano h. J Allergy Clin Immunol. 2011 May;127(5):1267-76.e6. doi: 10.1016/j.jaci.2010.12.1078. Epub 2011 Feb 18. J Allergy Clin Immunol. 2011. PMID: 21333342
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