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Empagliflozin restores lowered exercise endurance capacity via the activation of skeletal muscle fatty acid oxidation in a murine model of heart failure.
Nambu H, Takada S, Fukushima A, Matsumoto J, Kakutani N, Maekawa S, Shirakawa R, Nakano I, Furihata T, Katayama T, Yamanashi K, Obata Y, Saito A, Yokota T, Kinugawa S. Nambu H, et al. Among authors: nakano i. Eur J Pharmacol. 2020 Jan 5;866:172810. doi: 10.1016/j.ejphar.2019.172810. Epub 2019 Nov 15. Eur J Pharmacol. 2020. PMID: 31738936 Free article.
Inhibition of xanthine oxidase in the acute phase of myocardial infarction prevents skeletal muscle abnormalities and exercise intolerance.
Nambu H, Takada S, Maekawa S, Matsumoto J, Kakutani N, Furihata T, Shirakawa R, Katayama T, Nakajima T, Yamanashi K, Obata Y, Nakano I, Tsuda M, Saito A, Fukushima A, Yokota T, Nio-Kobayashi J, Yasui H, Higashikawa K, Kuge Y, Anzai T, Sabe H, Kinugawa S. Nambu H, et al. Among authors: nakano i. Cardiovasc Res. 2021 Feb 22;117(3):805-819. doi: 10.1093/cvr/cvaa127. Cardiovasc Res. 2021. PMID: 32402072
Type 2 diabetes is an independent predictor of lowered peak aerobic capacity in heart failure patients with non-reduced or reduced left ventricular ejection fraction.
Abe T, Yokota T, Fukushima A, Kakutani N, Katayama T, Shirakawa R, Maekawa S, Nambu H, Obata Y, Yamanashi K, Nakano I, Takada S, Yokota I, Okita K, Kinugawa S, Anzai T. Abe T, et al. Among authors: nakano i. Cardiovasc Diabetol. 2020 Sep 19;19(1):142. doi: 10.1186/s12933-020-01114-4. Cardiovasc Diabetol. 2020. PMID: 32950064 Free PMC article.
Brain-Derived Neurotrophic Factor Improves Impaired Fatty Acid Oxidation Via the Activation of Adenosine Monophosphate-Activated Protein Kinase-ɑ - Proliferator-Activated Receptor-r Coactivator-1ɑ Signaling in Skeletal Muscle of Mice With Heart Failure.
Matsumoto J, Takada S, Furihata T, Nambu H, Kakutani N, Maekawa S, Mizushima W, Nakano I, Fukushima A, Yokota T, Tanaka S, Handa H, Sabe H, Kinugawa S. Matsumoto J, et al. Among authors: nakano i. Circ Heart Fail. 2021 Jan;14(1):e005890. doi: 10.1161/CIRCHEARTFAILURE.119.005890. Epub 2020 Dec 28. Circ Heart Fail. 2021. PMID: 33356364
1,205 results