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KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development.
Tsukada Y, Ishitani T, Nakayama KI. Tsukada Y, et al. Among authors: nakayama ki. Genes Dev. 2010 Mar 1;24(5):432-7. doi: 10.1101/gad.1864410. Genes Dev. 2010. PMID: 20194436 Free PMC article.
Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress.
Matsumoto A, Tateishi Y, Onoyama I, Okita Y, Nakayama K, Nakayama KI. Matsumoto A, et al. Among authors: nakayama k, nakayama ki. Cancer Sci. 2011 Apr;102(4):749-55. doi: 10.1111/j.1349-7006.2011.01851.x. Epub 2011 Feb 9. Cancer Sci. 2011. PMID: 21205095
Expression of mouse Fbxw7 isoforms is regulated in a cell cycle- or p53-dependent manner.
Matsumoto A, Onoyama I, Nakayama KI. Matsumoto A, et al. Among authors: nakayama ki. Biochem Biophys Res Commun. 2006 Nov 10;350(1):114-9. doi: 10.1016/j.bbrc.2006.09.003. Epub 2006 Sep 12. Biochem Biophys Res Commun. 2006. PMID: 16989775
Fbxw7 acts as a critical fail-safe against premature loss of hematopoietic stem cells and development of T-ALL.
Matsuoka S, Oike Y, Onoyama I, Iwama A, Arai F, Takubo K, Mashimo Y, Oguro H, Nitta E, Ito K, Miyamoto K, Yoshiwara H, Hosokawa K, Nakamura Y, Gomei Y, Iwasaki H, Hayashi Y, Matsuzaki Y, Nakayama K, Ikeda Y, Hata A, Chiba S, Nakayama KI, Suda T. Matsuoka S, et al. Among authors: nakayama k, nakayama ki. Genes Dev. 2008 Apr 15;22(8):986-91. doi: 10.1101/gad.1621808. Epub 2008 Mar 26. Genes Dev. 2008. PMID: 18367647 Free PMC article.
Maternal TET3 is dispensable for embryonic development but is required for neonatal growth.
Tsukada Y, Akiyama T, Nakayama KI. Tsukada Y, et al. Among authors: nakayama ki. Sci Rep. 2015 Oct 28;5:15876. doi: 10.1038/srep15876. Sci Rep. 2015. PMID: 26507142 Free PMC article.
Anchoring of the 26S proteasome to the organellar membrane by FKBP38.
Nakagawa T, Shirane M, Iemura S, Natsume T, Nakayama KI. Nakagawa T, et al. Among authors: nakayama ki. Genes Cells. 2007 Jun;12(6):709-19. doi: 10.1111/j.1365-2443.2007.01086.x. Genes Cells. 2007. PMID: 17573772
Cell cycle-dependent regulation of the Skp2 promoter by GA-binding protein.
Imaki H, Nakayama K, Delehouzee S, Handa H, Kitagawa M, Kamura T, Nakayama KI. Imaki H, et al. Among authors: nakayama k, nakayama ki. Cancer Res. 2003 Aug 1;63(15):4607-13. Cancer Res. 2003. PMID: 12907639
Noncanonical Pathway for Regulation of CCL2 Expression by an mTORC1-FOXK1 Axis Promotes Recruitment of Tumor-Associated Macrophages.
Nakatsumi H, Matsumoto M, Nakayama KI. Nakatsumi H, et al. Among authors: nakayama ki. Cell Rep. 2017 Nov 28;21(9):2471-2486. doi: 10.1016/j.celrep.2017.11.014. Cell Rep. 2017. PMID: 29186685
UV Damage-Induced Phosphorylation of HBO1 Triggers CRL4DDB2-Mediated Degradation To Regulate Cell Proliferation.
Matsunuma R, Niida H, Ohhata T, Kitagawa K, Sakai S, Uchida C, Shiotani B, Matsumoto M, Nakayama KI, Ogura H, Shiiya N, Kitagawa M. Matsunuma R, et al. Among authors: nakayama ki. Mol Cell Biol. 2015 Nov 16;36(3):394-406. doi: 10.1128/MCB.00809-15. Print 2016 Feb 1. Mol Cell Biol. 2015. PMID: 26572825 Free PMC article.
Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
Nakajima T, Kitagawa K, Ohhata T, Sakai S, Uchida C, Shibata K, Minegishi N, Yumimoto K, Nakayama KI, Masumoto K, Katou F, Niida H, Kitagawa M. Nakajima T, et al. Among authors: nakayama ki. J Biol Chem. 2015 Apr 17;290(16):10368-81. doi: 10.1074/jbc.M114.613018. Epub 2015 Feb 10. J Biol Chem. 2015. PMID: 25670854 Free PMC article.
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