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Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo.
Zufferey R, Nagy D, Mandel RJ, Naldini L, Trono D. Zufferey R, et al. Nat Biotechnol. 1997 Sep;15(9):871-5. doi: 10.1038/nbt0997-871. Nat Biotechnol. 1997. PMID: 9306402
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector.
Naldini L, Blömer U, Gallay P, Ory D, Mulligan R, Gage FH, Verma IM, Trono D. Naldini L, et al. Science. 1996 Apr 12;272(5259):263-7. doi: 10.1126/science.272.5259.263. Science. 1996. PMID: 8602510
Applications of gene therapy to the CNS.
Blömer U, Naldini L, Verma IM, Trono D, Gage FH. Blömer U, et al. Hum Mol Genet. 1996;5 Spec No:1397-404. doi: 10.1093/hmg/5.supplement_1.1397. Hum Mol Genet. 1996. PMID: 8875243 Review.
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector.
Naldini L, Blömer U, Gage FH, Trono D, Verma IM. Naldini L, et al. Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11382-8. doi: 10.1073/pnas.93.21.11382. Proc Natl Acad Sci U S A. 1996. PMID: 8876144 Free PMC article.
Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector.
Blömer U, Naldini L, Kafri T, Trono D, Verma IM, Gage FH. Blömer U, et al. J Virol. 1997 Sep;71(9):6641-9. doi: 10.1128/JVI.71.9.6641-6649.1997. J Virol. 1997. PMID: 9261386 Free PMC article.
A third-generation lentivirus vector with a conditional packaging system.
Dull T, Zufferey R, Kelly M, Mandel RJ, Nguyen M, Trono D, Naldini L. Dull T, et al. J Virol. 1998 Nov;72(11):8463-71. doi: 10.1128/JVI.72.11.8463-8471.1998. J Virol. 1998. PMID: 9765382 Free PMC article.
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery.
Zufferey R, Dull T, Mandel RJ, Bukovsky A, Quiroz D, Naldini L, Trono D. Zufferey R, et al. J Virol. 1998 Dec;72(12):9873-80. doi: 10.1128/JVI.72.12.9873-9880.1998. J Virol. 1998. PMID: 9811723 Free PMC article.
Lentiviruses as gene transfer agents for delivery to non-dividing cells.
Naldini L. Naldini L. Curr Opin Biotechnol. 1998 Oct;9(5):457-63. doi: 10.1016/s0958-1669(98)80029-3. Curr Opin Biotechnol. 1998. PMID: 9821272 Review.
Stable transduction of quiescent CD34(+)CD38(-) human hematopoietic cells by HIV-1-based lentiviral vectors.
Case SS, Price MA, Jordan CT, Yu XJ, Wang L, Bauer G, Haas DL, Xu D, Stripecke R, Naldini L, Kohn DB, Crooks GM. Case SS, et al. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2988-93. doi: 10.1073/pnas.96.6.2988. Proc Natl Acad Sci U S A. 1999. PMID: 10077624 Free PMC article.
In vivo gene delivery by lentiviral vectors.
Naldini L. Naldini L. Thromb Haemost. 1999 Aug;82(2):552-4. Thromb Haemost. 1999. PMID: 10605750 Review. No abstract available.
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