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Irradiation-induced angiogenesis is associated with an MMP-9-miR-494-syndecan-1 regulatory loop in medulloblastoma cells.
Asuthkar S, Velpula KK, Nalla AK, Gogineni VR, Gondi CS, Rao JS. Asuthkar S, et al. Among authors: nalla ak. Oncogene. 2014 Apr 10;33(15):1922-33. doi: 10.1038/onc.2013.151. Epub 2013 Jun 3. Oncogene. 2014. PMID: 23728345
Apoptosis induced by knockdown of uPAR and MMP-9 is mediated by inactivation of EGFR/STAT3 signaling in medulloblastoma.
Kotipatruni RR, Nalla AK, Asuthkar S, Gondi CS, Dinh DH, Rao JS. Kotipatruni RR, et al. PLoS One. 2012;7(9):e44798. doi: 10.1371/journal.pone.0044798. Epub 2012 Sep 12. PLoS One. 2012. PMID: 22984561 Free PMC article.
Urokinase-type plasminogen activator receptor (uPAR)-mediated regulation of WNT/β-catenin signaling is enhanced in irradiated medulloblastoma cells.
Asuthkar S, Gondi CS, Nalla AK, Velpula KK, Gorantla B, Rao JS. Asuthkar S, et al. J Biol Chem. 2012 Jun 8;287(24):20576-89. doi: 10.1074/jbc.M112.348888. Epub 2012 Apr 16. J Biol Chem. 2012. PMID: 22511755 Free PMC article.
uPA and uPAR shRNA inhibit angiogenesis via enhanced secretion of SVEGFR1 independent of GM-CSF but dependent on TIMP-1 in endothelial and glioblastoma cells.
Raghu H, Nalla AK, Gondi CS, Gujrati M, Dinh DH, Rao JS. Raghu H, et al. Mol Oncol. 2012 Feb;6(1):33-47. doi: 10.1016/j.molonc.2011.11.008. Epub 2011 Nov 30. Mol Oncol. 2012. PMID: 22177802 Free PMC article.
Gadd45a sensitizes medulloblastoma cells to irradiation and suppresses MMP-9-mediated EMT.
Asuthkar S, Nalla AK, Gondi CS, Dinh DH, Gujrati M, Mohanam S, Rao JS. Asuthkar S, et al. Neuro Oncol. 2011 Oct;13(10):1059-73. doi: 10.1093/neuonc/nor109. Epub 2011 Aug 2. Neuro Oncol. 2011. PMID: 21813510 Free PMC article.
α3β1 integrin promotes radiation-induced migration of meningioma cells.
Gogineni VR, Nalla AK, Gupta R, Gujrati M, Klopfenstein JD, Mohanam S, Rao JS. Gogineni VR, et al. Int J Oncol. 2011 Jun;38(6):1615-24. doi: 10.3892/ijo.2011.987. Epub 2011 Mar 29. Int J Oncol. 2011. PMID: 21455571 Free PMC article.
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