Nam JO - Search Results

1

PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.

Tanjoni I, Walsh C, Uryu S, Tomar A, Nam JO, Mielgo A, Lim ST, Liang C, Koenig M, Sun C, Patel N, Kwok C, McMahon G, Stupack DG, Schlaepfer DD. Tanjoni I, et al. Among authors: nam jo. Cancer Biol Ther. 2010 May 15;9(10):764-77. doi: 10.4161/cbt.9.10.11434. Cancer Biol Ther. 2010. PMID: 20234191 Free PMC article.

2

Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival.

Lim ST, Miller NL, Nam JO, Chen XL, Lim Y, Schlaepfer DD. Lim ST, et al. Among authors: nam jo. J Biol Chem. 2010 Jan 15;285(3):1743-53. doi: 10.1074/jbc.M109.064212. Epub 2009 Oct 30. J Biol Chem. 2010. PMID: 19880522 Free PMC article.

3

Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models.

Walsh C, Tanjoni I, Uryu S, Tomar A, Nam JO, Luo H, Phillips A, Patel N, Kwok C, McMahon G, Stupack DG, Schlaepfer DD. Walsh C, et al. Among authors: nam jo. Cancer Biol Ther. 2010 May 15;9(10):778-90. doi: 10.4161/cbt.9.10.11433. Cancer Biol Ther. 2010. PMID: 20234193 Free PMC article.

4

p190RhoGEF (Rgnef) promotes colon carcinoma tumor progression via interaction with focal adhesion kinase.

Yu HG, Nam JO, Miller NL, Tanjoni I, Walsh C, Shi L, Kim L, Chen XL, Tomar A, Lim ST, Schlaepfer DD. Yu HG, et al. Among authors: nam jo. Cancer Res. 2011 Jan 15;71(2):360-70. doi: 10.1158/0008-5472.CAN-10-2894. Epub 2011 Jan 11. Cancer Res. 2011. PMID: 21224360 Free PMC article.

5

VEGF-induced vascular permeability is mediated by FAK.

Chen XL, Nam JO, Jean C, Lawson C, Walsh CT, Goka E, Lim ST, Tomar A, Tancioni I, Uryu S, Guan JL, Acevedo LM, Weis SM, Cheresh DA, Schlaepfer DD. Chen XL, et al. Among authors: nam jo. Dev Cell. 2012 Jan 17;22(1):146-57. doi: 10.1016/j.devcel.2011.11.002. Dev Cell. 2012. PMID: 22264731 Free PMC article.

6

Inhibition of endothelial FAK activity prevents tumor metastasis by enhancing barrier function.

Jean C, Chen XL, Nam JO, Tancioni I, Uryu S, Lawson C, Ward KK, Walsh CT, Miller NL, Ghassemian M, Turowski P, Dejana E, Weis S, Cheresh DA, Schlaepfer DD. Jean C, et al. Among authors: nam jo. J Cell Biol. 2014 Jan 20;204(2):247-63. doi: 10.1083/jcb.201307067. J Cell Biol. 2014. PMID: 24446483 Free PMC article.

7

Endothelial angiogenic activity and adipose angiogenesis is controlled by extracellular matrix protein TGFBI.

Lee SG, Kim JS, Kim HJ, Schlaepfer DD, Kim IS, Nam JO. Lee SG, et al. Among authors: nam jo. Sci Rep. 2021 May 6;11(1):9644. doi: 10.1038/s41598-021-88959-1. Sci Rep. 2021. PMID: 33958649 Free PMC article.

8

TGFBI remodels adipose metabolism by regulating the Notch-1 signaling pathway.

Lee SG, Chae J, Woo SM, Seo SU, Kim HJ, Kim SY, Schlaepfer DD, Kim IS, Park HS, Kwon TK, Nam JO. Lee SG, et al. Among authors: nam jo. Exp Mol Med. 2023 Mar;55(3):520-531. doi: 10.1038/s12276-023-00947-9. Epub 2023 Mar 1. Exp Mol Med. 2023. PMID: 36854775 Free PMC article.

9

The COOH-terminal end of R-Ras alters the motility and morphology of breast epithelial cells through Rho/Rho-kinase.

Jeong HW, Nam JO, Kim IS. Jeong HW, et al. Among authors: nam jo. Cancer Res. 2005 Jan 15;65(2):507-15. Cancer Res. 2005. PMID: 15695393

10

Antitumor effect of a transducible fusogenic peptide releasing multiple proapoptotic peptides by caspase-3.

Kwon MK, Nam JO, Park RW, Lee BH, Park JY, Byun YR, Kim SY, Kwon IC, Kim IS. Kwon MK, et al. Among authors: nam jo. Mol Cancer Ther. 2008 Jun;7(6):1514-22. doi: 10.1158/1535-7163.MCT-07-2009. Mol Cancer Ther. 2008. PMID: 18566222

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