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Mammalian P2X7 receptor pharmacology: comparison of recombinant mouse, rat and human P2X7 receptors.
Donnelly-Roberts DL, Namovic MT, Han P, Jarvis MF. Donnelly-Roberts DL, et al. Among authors: namovic mt. Br J Pharmacol. 2009 Aug;157(7):1203-14. doi: 10.1111/j.1476-5381.2009.00233.x. Epub 2009 Jun 22. Br J Pharmacol. 2009. PMID: 19558545 Free PMC article.
P2X7-related modulation of pathological nociception in rats.
McGaraughty S, Chu KL, Namovic MT, Donnelly-Roberts DL, Harris RR, Zhang XF, Shieh CC, Wismer CT, Zhu CZ, Gauvin DM, Fabiyi AC, Honore P, Gregg RJ, Kort ME, Nelson DW, Carroll WA, Marsh K, Faltynek CR, Jarvis MF. McGaraughty S, et al. Among authors: namovic mt. Neuroscience. 2007 Jun 8;146(4):1817-28. doi: 10.1016/j.neuroscience.2007.03.035. Epub 2007 May 3. Neuroscience. 2007. PMID: 17478048
Pharmacological modulation of eosinophil influx into the lungs of Brown Norway rats.
Namovic MT, Walsh RE, Goodfellow C, Harris RR, Carter GW, Bell RL. Namovic MT, et al. Eur J Pharmacol. 1996 Nov 7;315(1):81-8. doi: 10.1016/s0014-2999(96)00590-0. Eur J Pharmacol. 1996. PMID: 8960868
Pharmacological characterization of P2X7 receptors in rat peritoneal cells.
Chen YW, Donnelly-Roberts DL, Namovic MT, Gintant GA, Cox BF, Jarvis MF, Harris RR. Chen YW, et al. Among authors: namovic mt. Inflamm Res. 2005 Mar;54(3):119-26. doi: 10.1007/s00011-004-1332-7. Inflamm Res. 2005. PMID: 15883745
Reduced nicotinic receptor-mediated antinociception following in vivo antisense knock-down in rat.
Bitner RS, Nikkel AL, Curzon P, Donnelly-Roberts DL, Puttfarcken PS, Namovic M, Jacobs IC, Meyer MD, Decker MW. Bitner RS, et al. Among authors: namovic m. Brain Res. 2000 Jul 14;871(1):66-74. doi: 10.1016/s0006-8993(00)02442-2. Brain Res. 2000. PMID: 10882784
Synthesis and activity of N-cyanoguanidine-piperazine P2X7 antagonists.
Betschmann P, Bettencourt B, Donnelly-Roberts D, Friedman M, George J, Hirst G, Josephsohn N, Konopacki D, Li B, Maull J, Morytko MJ, Moore NS, Namovic M, Rafferty P, Salmeron-Garcia JA, Tarcsa E, Wang L, Woller K. Betschmann P, et al. Among authors: namovic m. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3848-51. doi: 10.1016/j.bmcl.2008.06.055. Epub 2008 Jun 20. Bioorg Med Chem Lett. 2008. PMID: 18595695
The antihyperalgesic activity of a selective P2X7 receptor antagonist, A-839977, is lost in IL-1alphabeta knockout mice.
Honore P, Donnelly-Roberts D, Namovic M, Zhong C, Wade C, Chandran P, Zhu C, Carroll W, Perez-Medrano A, Iwakura Y, Jarvis MF. Honore P, et al. Among authors: namovic m. Behav Brain Res. 2009 Dec 1;204(1):77-81. doi: 10.1016/j.bbr.2009.05.018. Epub 2009 May 21. Behav Brain Res. 2009. PMID: 19464323
Comparative analysis of inactivated-state block of N-type (Ca(v)2.2) calcium channels.
Vortherms TA, Swensen AM, Niforatos W, Limberis JT, Neelands TR, Janis RS, Thimmapaya R, Donnelly-Roberts DL, Namovic MT, Zhang D, Brent Putman C, Martin RL, Surowy CS, Jarvis MF, Scott VE. Vortherms TA, et al. Among authors: namovic mt. Inflamm Res. 2011 Jul;60(7):683-93. doi: 10.1007/s00011-011-0322-9. Epub 2011 Mar 11. Inflamm Res. 2011. PMID: 21394563
High throughput functional assays for P2X receptors.
Namovic MT, Jarvis MF, Donnelly-Roberts D. Namovic MT, et al. Curr Protoc Pharmacol. 2012 Jun;Chapter 9:Unit 9.15.. doi: 10.1002/0471141755.ph0915s57. Curr Protoc Pharmacol. 2012. PMID: 22684723
Novel and potent 3-(2,3-dichlorophenyl)-4-(benzyl)-4H-1,2,4-triazole P2X7 antagonists.
Carroll WA, Kalvin DM, Perez Medrano A, Florjancic AS, Wang Y, Donnelly-Roberts DL, Namovic MT, Grayson G, Honoré P, Jarvis MF. Carroll WA, et al. Among authors: namovic mt. Bioorg Med Chem Lett. 2007 Jul 15;17(14):4044-8. doi: 10.1016/j.bmcl.2007.04.075. Epub 2007 Apr 27. Bioorg Med Chem Lett. 2007. PMID: 17482819
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