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2010 1
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43 results

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Page 1
β-Amyloid induces microglial expression of GPC4 and APOE leading to increased neuronal tau pathology and toxicity.
Holmes BB, Weigel TK, Chung JM, Kaufman SK, Apresa BI, Byrnes JR, Kumru KS, Vaquer-Alicea J, Gupta A, Rose IVL, Zhang Y, Nana AL, Alter D, Grinberg LT, Spina S, Leung KK, Miller BL, Condello C, Kampmann M, Seeley WW, Coutinho-Budd JC, Wells JA. Holmes BB, et al. Among authors: nana al. Mol Neurodegener. 2025 Aug 29;20(1):96. doi: 10.1186/s13024-025-00883-4. Mol Neurodegener. 2025. PMID: 40883746 Free PMC article.
Brain transcriptomics highlight abundant gene expression and splicing alterations in non-neuronal cells in aFTLD-U.
Alidadiani S, Faura J, Wynants S, Peeters N, Van den Broeck M, De Witte L, Policarpo R, Cheung S, Pottier C, Ghayal NB, Mol MO, van Blitterswijk M, Udine E, DeJesus-Hernandez M, Baker M, Finch NA, Asmann YW, van Rooij JGJ, Nguyen AT, Ross Reichard R, Nana AL, Lopez OL, Boxer AL, Rosen HJ, Spina S, Herms J, Josephs KA, Petersen RC, Rissman RA, Hiniker A, Ang LC, Grinberg LT, Halliday GM, Boeve BF, Graff-Radford NR, Seelaar H, Neumann M, Kofler J, White CL 3rd, Seeley WW, van Swieten JC, Dickson DW, Mackenzie IRA, De Coster W, Rademakers R. Alidadiani S, et al. Among authors: nana al. Acta Neuropathol. 2025 Aug 10;150(1):17. doi: 10.1007/s00401-025-02919-x. Acta Neuropathol. 2025. PMID: 40783910 Free PMC article.
Opposing role of phagocytic receptors MERTK and AXL in Progranulin deficient FTD.
Clelland CD, Fan L, Saloner R, Etchegaray JI, Altobelli CR, Salomonsson S, Maltos AM, Sachdev A, Zhu J, Lee SI, Li Y, Zhou Y, Le D, Wang C, Carling G, Kodama L, Sayed F, Perez-Bermejo JA, Geier EG, Yokoyama JS, Rosen H, Nana AL, Spina S, Grinberg LT, Seeley WW, Elahi F, Boxer AL, Arkin MR, Gan L. Clelland CD, et al. Among authors: nana al. Commun Biol. 2025 Jul 1;8(1):971. doi: 10.1038/s42003-025-08368-2. Commun Biol. 2025. PMID: 40596721 Free PMC article.
Cell autonomous microglia defects in a stem cell model of frontotemporal dementia tau.
Iyer AK, Vermunt L, Mirfakhar FS, Minaya M, Acquarone M, Koppisetti RK, Renganathan A, You SF, Danhash EP, Schache KJ, Verbeck A, Galasso G, Lee SM, Huang G, Miller KJ, Marsh J, Nana AL, Spina S, Seeley WW, Grinberg LT, Temple S, Teunissen CE, Sato C, Karch CM. Iyer AK, et al. Among authors: nana al. Mol Psychiatry. 2025 Oct;30(10):4776-4791. doi: 10.1038/s41380-025-03073-2. Epub 2025 Jun 17. Mol Psychiatry. 2025. PMID: 40527900 Free PMC article.
Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing.
Pottier C, Küçükali F, Baker M, Batzler A, Jenkins GD, van Blitterswijk M, Vicente CT, De Coster W, Wynants S, Van de Walle P, Ross OA, Murray ME, Faura J, Haggarty SJ, van Rooij JG, Mol MO, Hsiung GR, Graff C, Öijerstedt L, Neumann M, Asmann Y, McDonnell SK, Baheti S, Josephs KA, Whitwell JL, Bieniek KF, Forsberg L, Heuer H, Lago AL, Geier EG, Yokoyama JS, Oddi AP, Flanagan M, Mao Q, Hodges JR, Kwok JB, Domoto-Reilly K, Synofzik M, Wilke C, Onyike C, Dickerson BC, Evers BM, Dugger BN, Munoz DG, Keith J, Zinman L, Rogaeva E, Suh E, Gefen T, Geula C, Weintraub S, Diehl-Schmid J, Farlow MR, Edbauer D, Woodruff BK, Caselli RJ, Donker Kaat LL, Huey ED, Reiman EM, Mead S, King A, Roeber S, Nana AL, Ertekin-Taner N, Knopman DS, Petersen RC, Petrucelli L, Uitti RJ, Wszolek ZK, Ramos EM, Grinberg LT, Tempini MLG, Rosen HJ, Spina S, Piguet O, Grossman M, Trojanowski JQ, Keene CD, Jin LW, Prudlo J, Geschwind DH, Rissman RA, Cruchaga C, Ghetti B, Halliday GM, Beach TG, Serrano GE, Arzberger T, Herms J, Boxer AL, Honig LS, Vonsattel JP, Lopez OL, Kofler J, White CL 3rd, Gearing M, Glass J, Rohrer JD, Irwin DJ, Lee EB, Van Deerlin V, Castellani R, Mesulam MM, Tartaglia MC, Finger EC, Tr… See abstract for full author list ➔ Pottier C, et al. Among authors: nana al. Nat Commun. 2025 Apr 25;16(1):3914. doi: 10.1038/s41467-025-59216-0. Nat Commun. 2025. PMID: 40280976 Free PMC article.
β-Amyloid Induces Microglial Expression of GPC4 and APOE Leading to Increased Neuronal Tau Pathology and Toxicity.
Holmes BB, Weigel TK, Chung JM, Kaufman SK, Apresa BI, Byrnes JR, Kumru KS, Vaquer-Alicea J, Gupta A, Rose IVL, Zhang Y, Nana AL, Alter D, Grinberg LT, Spina S, Leung KK, Condello C, Kampmann M, Seeley WW, Coutinho-Budd JC, Wells JA. Holmes BB, et al. Among authors: nana al. bioRxiv [Preprint]. 2025 Feb 25:2025.02.20.637701. doi: 10.1101/2025.02.20.637701. bioRxiv. 2025. Update in: Mol Neurodegener. 2025 Aug 29;20(1):96. doi: 10.1186/s13024-025-00883-4. PMID: 40060520 Free PMC article. Updated. Preprint.
Deciphering Distinct Genetic Risk Factors for FTLD-TDP Pathological Subtypes via Whole-Genome Sequencing.
Pottier C, Küçükali F, Baker M, Batzler A, Jenkins GD, van Blitterswijk M, Vicente CT, De Coster W, Wynants S, Van de Walle P, Ross OA, Murray ME, Faura J, Haggarty SJ, van Rooij JG, Mol MO, Hsiung GR, Graff C, Öijerstedt L, Neumann M, Asmann Y, McDonnell SK, Baheti S, Josephs KA, Whitwell JL, Bieniek KF, Forsberg L, Heuer H, Lago AL, Geier EG, Yokoyama JS, Oddi AP, Flanagan M, Mao Q, Hodges JR, Kwok JB, Domoto-Reilly K, Synofzik M, Wilke C, Onyike C, Dickerson BC, Evers BM, Dugger BN, Munoz DG, Keith J, Zinman L, Rogaeva E, Suh E, Gefen T, Geula C, Weintraub S, Diehl-Schmid J, Farlow MR, Edbauer D, Woodruff BK, Caselli RJ, Donker Kaat LL, Huey ED, Reiman EM, Mead S, King A, Roeber S, Nana AL, Ertekin-Taner N, Knopman DS, Petersen RC, Petrucelli L, Uitti RJ, Wszolek ZK, Ramos EM, Grinberg LT, Gorno Tempini ML, Rosen HJ, Spina S, Piguet O, Grossman M, Trojanowski JQ, Keene DC, Lee-Way J, Prudlo J, Geschwind DH, Rissman RA, Cruchaga C, Ghetti B, Halliday GM, Beach TG, Serrano GE, Arzberger T, Herms J, Boxer AL, Honig LS, Vonsattel JP, Lopez OL, Kofler J, White CL, Gearing M, Glass J, Rohrer JD, Irwin DJ, Lee EB, Van Deerlin V, Castellani R, Mesulam MM, Tartaglia MC, Finger EC… See abstract for full author list ➔ Pottier C, et al. Among authors: nana al. medRxiv [Preprint]. 2024 Jun 25:2024.06.24.24309088. doi: 10.1101/2024.06.24.24309088. medRxiv. 2024. Update in: Nat Commun. 2025 Apr 25;16(1):3914. doi: 10.1038/s41467-025-59216-0. PMID: 38978643 Free PMC article. Updated. Preprint.
Cell autonomous microglia defects in a stem cell model of frontotemporal dementia.
Iyer AK, Vermunt L, Mirfakhar FS, Minaya M, Acquarone M, Koppisetti RK, Renganathan A, You SF, Danhash EP, Verbeck A, Galasso G, Lee SM, Marsh J, Nana AL, Spina S, Seeley WW, Grinberg LT, Temple S, Teunissen CE, Sato C, Karch CM. Iyer AK, et al. Among authors: nana al. medRxiv [Preprint]. 2024 May 16:2024.05.15.24307444. doi: 10.1101/2024.05.15.24307444. medRxiv. 2024. Update in: Mol Psychiatry. 2025 Oct;30(10):4776-4791. doi: 10.1038/s41380-025-03073-2. PMID: 38798451 Free PMC article. Updated. Preprint.
Mutant tau and stress lead to downregulation of long noncoding RNA, SNHG8.
Bhagat R, Minaya MA, Renganathan A, Mehra M, Marsh J, Martinez R, Eteleeb AM, Nana AL, Spina S, Seeley WW, Grinberg LT, Karch CM. Bhagat R, et al. Among authors: nana al. Mol Psychiatry. 2023 Nov;28(11):4489. doi: 10.1038/s41380-023-02328-0. Mol Psychiatry. 2023. PMID: 38443679 Free PMC article. No abstract available.
43 results