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Stable drug encapsulation in micelles and microemulsions.
Narang AS, Delmarre D, Gao D. Narang AS, et al. Int J Pharm. 2007 Dec 10;345(1-2):9-25. doi: 10.1016/j.ijpharm.2007.08.057. Epub 2007 Sep 8. Int J Pharm. 2007. PMID: 17945446 Review.
Effect of force feeder on tablet strength during compression.
Narang AS, Rao VM, Guo H, Lu J, Desai DS. Narang AS, et al. Int J Pharm. 2010 Nov 30;401(1-2):7-15. doi: 10.1016/j.ijpharm.2010.08.027. Epub 2010 Sep 9. Int J Pharm. 2010. PMID: 20816733
Role of tumor vascular architecture in drug delivery.
Narang AS, Varia S. Narang AS, et al. Adv Drug Deliv Rev. 2011 Jul 18;63(8):640-58. doi: 10.1016/j.addr.2011.04.002. Epub 2011 Apr 14. Adv Drug Deliv Rev. 2011. PMID: 21514334 Review.
Reactive impurities in excipients: profiling, identification and mitigation of drug-excipient incompatibility.
Wu Y, Levons J, Narang AS, Raghavan K, Rao VM. Wu Y, et al. AAPS PharmSciTech. 2011 Dec;12(4):1248-63. doi: 10.1208/s12249-011-9677-z. Epub 2011 Sep 27. AAPS PharmSciTech. 2011. PMID: 21948318 Free PMC article. Review.
Reversible and pH-dependent weak drug-excipient binding does not affect oral bioavailability of high dose drugs.
Narang AS, Yamniuk AP, Zhang L, Comezoglu SN, Bindra DS, Varia S, Doyle ML, Badawy S. Narang AS, et al. J Pharm Pharmacol. 2012 Apr;64(4):553-65. doi: 10.1111/j.2042-7158.2011.01435.x. Epub 2012 Jan 13. J Pharm Pharmacol. 2012. PMID: 22420661
We investigated whether nondisruption of interaction by physiological salt concentration was an adequate predictor of its biorelevance using the binding of a model amine high dose drug brivanib alaninate (BA) to croscarmellose sodium (CCS) as an example. METHODS: BA was fo …
We investigated whether nondisruption of interaction by physiological salt concentration was an adequate predictor of its biorelevance using …
Impact of excipient interactions on solid dosage form stability.
Narang AS, Desai D, Badawy S. Narang AS, et al. Pharm Res. 2012 Oct;29(10):2660-83. doi: 10.1007/s11095-012-0782-9. Epub 2012 Jun 16. Pharm Res. 2012. PMID: 22707362 Review.
Drug-excipient interactions in solid dosage forms can affect drug product stability in physical aspects such as organoleptic changes and dissolution slowdown, or chemically by causing drug degradation. ...
Drug-excipient interactions in solid dosage forms can affect drug product stability in physical aspects such as organoleptic changes …
Pharmaceutical development and regulatory considerations for nanoparticles and nanoparticulate drug delivery systems.
Narang AS, Chang RK, Hussain MA. Narang AS, et al. J Pharm Sci. 2013 Nov;102(11):3867-82. doi: 10.1002/jps.23691. Epub 2013 Aug 23. J Pharm Sci. 2013. PMID: 24037829
Pharmaceutical nanomaterials (NMs) encompass a wide variety of materials including drug nanoparticles (NPs), which can be amorphous or crystalline; or nanoparticulate drug delivery systems, such as micelles, microemulsions, liposomes, drug-polymer conjugates, and antibody- …
Pharmaceutical nanomaterials (NMs) encompass a wide variety of materials including drug nanoparticles (NPs), which can be amorphous or cryst …
Quality by design development of brivanib alaninate tablets: degradant and moisture control strategy.
Badawy SI, Lin J, Gokhale M, Desai S, Nesarikar VV, LaMarche KR, Subramanian GA, Narang AS. Badawy SI, et al. Int J Pharm. 2014 Jul 20;469(1):111-20. doi: 10.1016/j.ijpharm.2014.04.059. Epub 2014 Apr 26. Int J Pharm. 2014. PMID: 24780101
The BMS-540215 amount versus time profile was simulated using a kinetic model for the formation of BMS-540215 as function of relative humidity in the environment and a sorption-desorptiom moisture transfer model for the relative humidity inside the package. ...
The BMS-540215 amount versus time profile was simulated using a kinetic model for the formation of BMS-540215 as function of relative …
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