Narendra D - Search Results

1

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy.

Narendra D, Tanaka A, Suen DF, Youle RJ. Narendra D, et al. J Cell Biol. 2008 Dec 1;183(5):795-803. doi: 10.1083/jcb.200809125. Epub 2008 Nov 24. J Cell Biol. 2008. PMID: 19029340 Free PMC article.

2

Parkin-induced mitophagy in the pathogenesis of Parkinson disease.

Narendra D, Tanaka A, Suen DF, Youle RJ. Narendra D, et al. Autophagy. 2009 Jul;5(5):706-8. doi: 10.4161/auto.5.5.8505. Epub 2009 Jul 22. Autophagy. 2009. PMID: 19377297

3

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.

Narendra DP, Jin SM, Tanaka A, Suen DF, Gautier CA, Shen J, Cookson MR, Youle RJ. Narendra DP, et al. PLoS Biol. 2010 Jan 26;8(1):e1000298. doi: 10.1371/journal.pbio.1000298. PLoS Biol. 2010. PMID: 20126261 Free PMC article.

4

Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells.

Suen DF, Narendra DP, Tanaka A, Manfredi G, Youle RJ. Suen DF, et al. Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11835-40. doi: 10.1073/pnas.0914569107. Epub 2010 Jun 14. Proc Natl Acad Sci U S A. 2010. PMID: 20547844 Free PMC article.

5

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both.

Narendra D, Kane LA, Hauser DN, Fearnley IM, Youle RJ. Narendra D, et al. Autophagy. 2010 Nov;6(8):1090-106. doi: 10.4161/auto.6.8.13426. Autophagy. 2010. PMID: 20890124 Free PMC article.

6

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL.

Jin SM, Lazarou M, Wang C, Kane LA, Narendra DP, Youle RJ. Jin SM, et al. J Cell Biol. 2010 Nov 29;191(5):933-42. doi: 10.1083/jcb.201008084. J Cell Biol. 2010. PMID: 21115803 Free PMC article.

7

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin.

Tanaka A, Cleland MM, Xu S, Narendra DP, Suen DF, Karbowski M, Youle RJ. Tanaka A, et al. J Cell Biol. 2010 Dec 27;191(7):1367-80. doi: 10.1083/jcb.201007013. Epub 2010 Dec 20. J Cell Biol. 2010. PMID: 21173115 Free PMC article.

8

Mechanisms of mitophagy.

Youle RJ, Narendra DP. Youle RJ, et al. Nat Rev Mol Cell Biol. 2011 Jan;12(1):9-14. doi: 10.1038/nrm3028. Nat Rev Mol Cell Biol. 2011. PMID: 21179058 Free PMC article. Review.

9

Targeting mitochondrial dysfunction: role for PINK1 and Parkin in mitochondrial quality control.

Narendra DP, Youle RJ. Narendra DP, et al. Antioxid Redox Signal. 2011 May 15;14(10):1929-38. doi: 10.1089/ars.2010.3799. Epub 2011 Mar 3. Antioxid Redox Signal. 2011. PMID: 21194381 Free PMC article. Review.

10

Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism.

Narendra D, Walker JE, Youle R. Narendra D, et al. Cold Spring Harb Perspect Biol. 2012 Nov 1;4(11):a011338. doi: 10.1101/cshperspect.a011338. Cold Spring Harb Perspect Biol. 2012. PMID: 23125018 Free PMC article.

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