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Oxidation of 5-methoxy-N,N-diisopropyltryptamine in rat liver microsomes and recombinant cytochrome P450 enzymes.
Narimatsu S, Yonemoto R, Masuda K, Katsu T, Asanuma M, Kamata T, Katagi M, Tsuchihashi H, Kumamoto T, Ishikawa T, Naito S, Yamano S, Hanioka N. Narimatsu S, et al. Biochem Pharmacol. 2008 Feb 1;75(3):752-60. doi: 10.1016/j.bcp.2007.09.019. Epub 2007 Sep 29. Biochem Pharmacol. 2008. PMID: 17980859
This metabolic profile is different from our previous findings in human liver microsomal fractions, in which the aromatic ring O-demethylation was the major pathway whereas the side-chain N-deisopropylation was minor [Narimatsu S, Yonemoto R, Saito K, Takaya K, Kuma …
This metabolic profile is different from our previous findings in human liver microsomal fractions, in which the aromatic ring O-demethylati …
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