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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1959 2
1960 1
1962 1
1963 1
1965 2
1969 2
1970 2
1971 2
1972 1
1973 1
1974 1
1975 1
1976 2
1977 2
1978 2
1979 4
1980 6
1981 1
1982 3
1983 7
1984 3
1985 8
1986 9
1987 6
1988 12
1989 8
1990 14
1991 11
1992 6
1993 9
1994 21
1995 19
1996 18
1997 21
1998 31
1999 39
2000 50
2001 38
2002 49
2003 66
2004 79
2005 82
2006 93
2007 106
2008 115
2009 95
2010 139
2011 142
2012 164
2013 179
2014 187
2015 172
2016 196
2017 222
2018 247
2019 244
2020 334
2021 339
2022 7
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3,228 results
Results by year
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Page 1
Naringenin as a potential immunomodulator in therapeutics.
Zeng W, Jin L, Zhang F, Zhang C, Liang W. Zeng W, et al. Pharmacol Res. 2018 Sep;135:122-126. doi: 10.1016/j.phrs.2018.08.002. Epub 2018 Aug 3. Pharmacol Res. 2018. PMID: 30081177 Review.
The mechanism of action of naringenin is not completely understood but recent mechanistic studies revealed that naringenin suppresses inflammatory cytokine production through both transcriptional and post-transcriptional mechanisms. ...Therefore, naringenin m …
The mechanism of action of naringenin is not completely understood but recent mechanistic studies revealed that naringenin sup …
Naringenin, a flavanone with antiviral and anti-inflammatory effects: A promising treatment strategy against COVID-19.
Tutunchi H, Naeini F, Ostadrahimi A, Hosseinzadeh-Attar MJ. Tutunchi H, et al. Phytother Res. 2020 Dec;34(12):3137-3147. doi: 10.1002/ptr.6781. Epub 2020 Jul 2. Phytother Res. 2020. PMID: 32613637 Free PMC article. Review.
In this review, the promising effects and possible mechanisms of action of naringenin, a citrus-derived flavonoid, against COVID-19 were discussed. ...The antiviral activity of the flavanone naringenin against some viruses has also been reported. On the whole, the f …
In this review, the promising effects and possible mechanisms of action of naringenin, a citrus-derived flavonoid, against COVID-19 w …
Beneficial effects of naringenin in liver diseases: Molecular mechanisms.
Hernández-Aquino E, Muriel P. Hernández-Aquino E, et al. World J Gastroenterol. 2018 Apr 28;24(16):1679-1707. doi: 10.3748/wjg.v24.i16.1679. World J Gastroenterol. 2018. PMID: 29713125 Free PMC article. Review.
Naringenin is safe and acts by targeting multiple proteins. However, it possesses low bioavailability and high intestinal metabolism. In this regard, formulations, such as nanoparticles or liposomes, have been developed to improve naringenin bioavailability. We conc
Naringenin is safe and acts by targeting multiple proteins. However, it possesses low bioavailability and high intestinal metabolism.
Naringenin attenuates non-alcoholic fatty liver disease by down-regulating the NLRP3/NF-kappaB pathway in mice.
Wang Q, Ou Y, Hu G, Wen C, Yue S, Chen C, Xu L, Xie J, Dai H, Xiao H, Zhang Y, Qi R. Wang Q, et al. Br J Pharmacol. 2020 Apr;177(8):1806-1821. doi: 10.1111/bph.14938. Epub 2020 Jan 30. Br J Pharmacol. 2020. PMID: 31758699 Free PMC article.
Treating the HepG2 cells with naringenin or NLRP3 inhibitor MCC950 reduced lipid accumulation. Naringenin inhibited activation of the NLRP3/NF-kappaB pathway stimulated by OA together with LPS. In KCs isolated from WT mice, naringenin inhibited NLRP3 expressi …
Treating the HepG2 cells with naringenin or NLRP3 inhibitor MCC950 reduced lipid accumulation. Naringenin inhibited activation …
Naringenin reduces inflammatory pain in mice.
Pinho-Ribeiro FA, Zarpelon AC, Fattori V, Manchope MF, Mizokami SS, Casagrande R, Verri WA Jr. Pinho-Ribeiro FA, et al. Neuropharmacology. 2016 Jun;105:508-519. doi: 10.1016/j.neuropharm.2016.02.019. Epub 2016 Feb 18. Neuropharmacology. 2016. PMID: 26907804
Naringenin is a flavonoid widely consumed by humans that present anti-inflammatory activity and low toxicity. Recently, the analgesic effect of naringenin has been demonstrated in neuropathic pain models. Herein, we tested the analgesic effects of naringenin
Naringenin is a flavonoid widely consumed by humans that present anti-inflammatory activity and low toxicity. Recently, the analgesic
Naringenin and naringin in cardiovascular disease prevention: A preclinical review.
Heidary Moghaddam R, Samimi Z, Moradi SZ, Little PJ, Xu S, Farzaei MH. Heidary Moghaddam R, et al. Eur J Pharmacol. 2020 Nov 15;887:173535. doi: 10.1016/j.ejphar.2020.173535. Epub 2020 Sep 8. Eur J Pharmacol. 2020. PMID: 32910944 Review.
In this review, based on the latest evidence, we present a summary of the impact of naringin, and naringenin on cardiovascular disease, and analyze and discuss the basic roles of naringin and naringenin and their mechanisms of actions in cardiovascular disease and o …
In this review, based on the latest evidence, we present a summary of the impact of naringin, and naringenin on cardiovascular diseas …
Antidiabetic Properties of Naringenin: A Citrus Fruit Polyphenol.
Den Hartogh DJ, Tsiani E. Den Hartogh DJ, et al. Biomolecules. 2019 Mar 12;9(3):99. doi: 10.3390/biom9030099. Biomolecules. 2019. PMID: 30871083 Free PMC article. Review.
In recent years, epidemiological studies have suggested that diets rich in vegetables and fruits are associated with health benefits including protection against insulin resistance and T2DM. Naringenin, a citrus flavanone, has been reported to have antioxidant, anti-inflam …
In recent years, epidemiological studies have suggested that diets rich in vegetables and fruits are associated with health benefits includi …
Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe(-/-)mice: role of SIRT1.
Hua YQ, Zeng Y, Xu J, Xu XL. Hua YQ, et al. Phytomedicine. 2021 Jan;81:153412. doi: 10.1016/j.phymed.2020.153412. Epub 2020 Nov 18. Phytomedicine. 2021. PMID: 33234364
BACKGROUND: Naringenin is naturally isolated from citrus fruits possessing many pharmacological activities. However, little is known about the effect of naringenin on nonalcoholic steatohepatitis (NASH) in the model of metabolic syndrome. ...
BACKGROUND: Naringenin is naturally isolated from citrus fruits possessing many pharmacological activities. However, little is known …
Pharmacokinetic, pharmacodynamic and formulations aspects of Naringenin: An update.
Joshi R, Kulkarni YA, Wairkar S. Joshi R, et al. Life Sci. 2018 Dec 15;215:43-56. doi: 10.1016/j.lfs.2018.10.066. Epub 2018 Nov 1. Life Sci. 2018. PMID: 30391464 Review.
Furthermore, the review also focuses on molecular level mechanisms of Naringenin for its therapeutic effect. Various attempts have been made to formulate advanced dosage forms to address issue of solubility of Naringenin. Systematic review of data published on formu …
Furthermore, the review also focuses on molecular level mechanisms of Naringenin for its therapeutic effect. Various attempts have be …
Naringenin and its Nano-formulations for Fatty Liver: Cellular Modes of Action and Clinical Perspective.
Zobeiri M, Belwal T, Parvizi F, Naseri R, Farzaei MH, Nabavi SF, Sureda A, Nabavi SM. Zobeiri M, et al. Curr Pharm Biotechnol. 2018;19(3):196-205. doi: 10.2174/1389201019666180514170122. Curr Pharm Biotechnol. 2018. PMID: 29766801 Review.
METHODS: In the present review, we discuss the effects of naringenin and its nano-formulations against fatty liver disease and the proposed molecular mechanism of action. ...Naringenin-loaded nanoparticles have been used to solve the limited stability, solubility, b …
METHODS: In the present review, we discuss the effects of naringenin and its nano-formulations against fatty liver disease and the pr …
3,228 results