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The efficacy of siRNAs against hepatitis C virus is strongly influenced by structure and target site accessibility.
Sagan SM, Nasheri N, Luebbert C, Pezacki JP. Sagan SM, et al. Among authors: nasheri n. Chem Biol. 2010 May 28;17(5):515-27. doi: 10.1016/j.chembiol.2010.04.011. Chem Biol. 2010. PMID: 20534349
Competing roles of microRNA-122 recognition elements in hepatitis C virus RNA.
Nasheri N, Singaravelu R, Goodmurphy M, Lyn RK, Pezacki JP. Nasheri N, et al. Virology. 2011 Feb 20;410(2):336-44. doi: 10.1016/j.virol.2010.11.015. Epub 2010 Dec 24. Virology. 2011. PMID: 21185047
An enzyme-linked assay for the rapid quantification of microRNAs based on the viral suppressor of RNA silencing protein p19.
Nasheri N, Cheng J, Singaravelu R, Wu P, McDermott MT, Pezacki JP. Nasheri N, et al. Anal Biochem. 2011 May 15;412(2):165-72. doi: 10.1016/j.ab.2011.01.030. Epub 2011 Feb 1. Anal Biochem. 2011. PMID: 21284927
Enhanced specificity of the viral suppressor of RNA silencing protein p19 toward sequestering of human microRNA-122.
Cheng J, Danielson DC, Nasheri N, Singaravelu R, Pezacki JP. Cheng J, et al. Among authors: nasheri n. Biochemistry. 2011 Sep 13;50(36):7745-55. doi: 10.1021/bi2008273. Epub 2011 Aug 17. Biochemistry. 2011. PMID: 21819044
Activity-based protein profiling of host-virus interactions.
Blais DR, Nasheri N, McKay CS, Legault MC, Pezacki JP. Blais DR, et al. Among authors: nasheri n. Trends Biotechnol. 2012 Feb;30(2):89-99. doi: 10.1016/j.tibtech.2011.08.001. Epub 2011 Sep 22. Trends Biotechnol. 2012. PMID: 21944551 Free PMC article. Review.
Design and screening of siRNAs against highly structured RNA targets.
Nasheri N, Pezacki JP, Sagan SM. Nasheri N, et al. Methods Mol Biol. 2013;942:69-86. doi: 10.1007/978-1-62703-119-6_4. Methods Mol Biol. 2013. PMID: 23027046
Modulation of fatty acid synthase enzyme activity and expression during hepatitis C virus replication.
Nasheri N, Joyce M, Rouleau Y, Yang P, Yao S, Tyrrell DL, Pezacki JP. Nasheri N, et al. Chem Biol. 2013 Apr 18;20(4):570-82. doi: 10.1016/j.chembiol.2013.03.014. Chem Biol. 2013. PMID: 23601646
Hepatitis C virus induced up-regulation of microRNA-27: a novel mechanism for hepatic steatosis.
Singaravelu R, Chen R, Lyn RK, Jones DM, O'Hara S, Rouleau Y, Cheng J, Srinivasan P, Nasheri N, Russell RS, Tyrrell DL, Pezacki JP. Singaravelu R, et al. Among authors: nasheri n. Hepatology. 2014 Jan;59(1):98-108. doi: 10.1002/hep.26634. Epub 2013 Nov 19. Hepatology. 2014. PMID: 23897856
A new chemical probe for phosphatidylinositol kinase activity.
Sherratt AR, Nasheri N, McKay CS, O'Hara S, Hunt A, Ning Z, Figeys D, Goto NK, Pezacki JP. Sherratt AR, et al. Among authors: nasheri n. Chembiochem. 2014 Jun 16;15(9):1253-6. doi: 10.1002/cbic.201402155. Epub 2014 May 21. Chembiochem. 2014. PMID: 24850173
Hydrophobic triaryl-substituted β-lactams as activity-based probes for profiling eukaryotic enzymes and host-pathogen interactions.
Nasheri N, McKay CS, Fulton K, Twine S, Powdrill MH, Sherratt AR, Pezacki JP. Nasheri N, et al. Chembiochem. 2014 Oct 13;15(15):2195-200. doi: 10.1002/cbic.201402097. Epub 2014 Sep 1. Chembiochem. 2014. PMID: 25179744 No abstract available.
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