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Single-cell analysis identifies Ifi27l2a as a gene regulator of microglial inflammation in the context of aging and stroke in mice.
Kim GS, Harmon E, Gutierrez MC, Kim S, Vance L, Burrous H, Stephenson JM, Chauhan A, Banerjee A, Wise Z, Doan A, Ahn J, Wu T, Bautista-Garrido J, Lee J, Tan C, Jung JE, McCullough LD, Wythe JD, Marrelli SP. Kim GS, et al. Nat Commun. 2025 Feb 14;16(1):1639. doi: 10.1038/s41467-025-56847-1. Nat Commun. 2025. PMID: 39953063 Free PMC article.
Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis.
Maiques O, Sallan MC, Laddach R, Pandya P, Varela A, Crosas-Molist E, Barcelo J, Courbot O, Liu Y, Graziani V, Arafat Y, Sewell J, Rodriguez-Hernandez I, Fanshawe B, Jung-Garcia Y, Imbert PR, Grasset EM, Albrengues J, Santacana M, Macià A, Tarragona J, Matias-Guiu X, Marti RM, Tsoka S, Gaggioli C, Orgaz JL, Fruhwirth GO, Wallberg F, Betteridge K, Reyes-Aldasoro CC, Haider S, Braun A, Karagiannis SN, Elosegui-Artola A, Sanz-Moreno V. Maiques O, et al. Nat Commun. 2025 Feb 14;16(1):1394. doi: 10.1038/s41467-025-56299-7. Nat Commun. 2025. PMID: 39952917 Free PMC article.
Learning and actioning general principles of cancer cell drug sensitivity.
Carli F, Di Chiaro P, Morelli M, Arora C, Bisceglia L, De Oliveira Rosa N, Cortesi A, Franceschi S, Lessi F, Di Stefano AL, Santonocito OS, Pasqualetti F, Aretini P, Miglionico P, Diaferia GR, Giannotti F, Liò P, Duran-Frigola M, Mazzanti CM, Natoli G, Raimondi F. Carli F, et al. Nat Commun. 2025 Feb 15;16(1):1654. doi: 10.1038/s41467-025-56827-5. Nat Commun. 2025. PMID: 39952993 Free PMC article.
34 results