Nathans RS - Search Results

1

Design and synthesis of HIV-1 protease inhibitors incorporating oxazolidinones as P2/P2' ligands in pseudosymmetric dipeptide isosteres.

Reddy GS, Ali A, Nalam MN, Anjum SG, Cao H, Nathans RS, Schiffer CA, Rana TM. Reddy GS, et al. Among authors: nathans rs. J Med Chem. 2007 Sep 6;50(18):4316-28. doi: 10.1021/jm070284z. Epub 2007 Aug 16. J Med Chem. 2007. PMID: 17696512 Free PMC article.

2

Synthesis and structure-activity relationship studies of HIV-1 virion infectivity factor (Vif) inhibitors that block viral replication.

Ali A, Wang J, Nathans RS, Cao H, Sharova N, Stevenson M, Rana TM. Ali A, et al. Among authors: nathans rs. ChemMedChem. 2012 Jul;7(7):1217-29. doi: 10.1002/cmdc.201200079. Epub 2012 May 3. ChemMedChem. 2012. PMID: 22555953 Free PMC article.

3

Small-molecule inhibition of HIV-1 Vif.

Nathans R, Cao H, Sharova N, Ali A, Sharkey M, Stranska R, Stevenson M, Rana TM. Nathans R, et al. Nat Biotechnol. 2008 Oct;26(10):1187-92. doi: 10.1038/nbt.1496. Epub 2008 Sep 21. Nat Biotechnol. 2008. PMID: 18806783 Free PMC article.

4

Cellular microRNA and P bodies modulate host-HIV-1 interactions.

Nathans R, Chu CY, Serquina AK, Lu CC, Cao H, Rana TM. Nathans R, et al. Mol Cell. 2009 Jun 26;34(6):696-709. doi: 10.1016/j.molcel.2009.06.003. Mol Cell. 2009. PMID: 19560422 Free PMC article.

5

P-TEFb kinase complex phosphorylates histone H1 to regulate expression of cellular and HIV-1 genes.

O'Brien SK, Cao H, Nathans R, Ali A, Rana TM. O'Brien SK, et al. J Biol Chem. 2010 Sep 24;285(39):29713-20. doi: 10.1074/jbc.M110.125997. Epub 2010 Jun 15. J Biol Chem. 2010. PMID: 20551309 Free PMC article.

6

Identification of flavopiridol analogues that selectively inhibit positive transcription elongation factor (P-TEFb) and block HIV-1 replication.

Ali A, Ghosh A, Nathans RS, Sharova N, O'Brien S, Cao H, Stevenson M, Rana TM. Ali A, et al. Among authors: nathans rs. Chembiochem. 2009 Aug 17;10(12):2072-80. doi: 10.1002/cbic.200900303. Chembiochem. 2009. PMID: 19603446 Free PMC article.

7

Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.

Xie Y, Avello M, Schirle M, McWhinnie E, Feng Y, Bric-Furlong E, Wilson C, Nathans R, Zhang J, Kirschner MW, Huang SM, Cong F. Xie Y, et al. J Biol Chem. 2013 Feb 1;288(5):2976-85. doi: 10.1074/jbc.M112.430066. Epub 2012 Nov 26. J Biol Chem. 2013. PMID: 23184937 Free PMC article.

8

Activation of a rel-A/CEBP-beta-related transcription factor heteromer by PGG-glucan in a murine monocytic cell line.

Adams DS, Nathans R, Pero SC, Sen A, Wakshull E. Adams DS, et al. J Cell Biochem. 2000 Mar;77(2):221-33. doi: 10.1002/(sici)1097-4644(20000501)77:2<221::aid-jcb6>3.0.co;2-v. J Cell Biochem. 2000. PMID: 10723089

9

PGG-Glucan activates NF-kappaB-like and NF-IL-6-like transcription factor complexes in a murine monocytic cell line.

Adams DS, Pero SC, Petro JB, Nathans R, Mackin WM, Wakshull E. Adams DS, et al. J Leukoc Biol. 1997 Dec;62(6):865-73. doi: 10.1002/jlb.62.6.865. J Leukoc Biol. 1997. PMID: 9400829

10

PGG-glucan, a soluble beta-(1,3)-glucan, enhances the oxidative burst response, microbicidal activity, and activates an NF-kappa B-like factor in human PMN: evidence for a glycosphingolipid beta-(1,3)-glucan receptor.

Wakshull E, Brunke-Reese D, Lindermuth J, Fisette L, Nathans RS, Crowley JJ, Tufts JC, Zimmerman J, Mackin W, Adams DS. Wakshull E, et al. Among authors: nathans rs. Immunopharmacology. 1999 Feb;41(2):89-107. doi: 10.1016/s0162-3109(98)00059-9. Immunopharmacology. 1999. PMID: 10102791

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