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Page 1
Natural killer cell therapies.
Vivier E, Rebuffet L, Narni-Mancinelli E, Cornen S, Igarashi RY, Fantin VR. Vivier E, et al. Nature. 2024 Feb;626(8000):727-736. doi: 10.1038/s41586-023-06945-1. Epub 2024 Feb 21. Nature. 2024. PMID: 38383621 Review.
Targeted protein degradation via intramolecular bivalent glues.
Hsia O, Hinterndorfer M, Cowan AD, Iso K, Ishida T, Sundaramoorthy R, Nakasone MA, Imrichova H, Schätz C, Rukavina A, Husnjak K, Wegner M, Correa-Sáez A, Craigon C, Casement R, Maniaci C, Testa A, Kaulich M, Dikic I, Winter GE, Ciulli A. Hsia O, et al. Nature. 2024 Mar;627(8002):204-211. doi: 10.1038/s41586-024-07089-6. Epub 2024 Feb 21. Nature. 2024. PMID: 38383787 Free PMC article.
IL-10 constrains sphingolipid metabolism to limit inflammation.
York AG, Skadow MH, Oh J, Qu R, Zhou QD, Hsieh WY, Mowel WK, Brewer JR, Kaffe E, Williams KJ, Kluger Y, Smale ST, Crawford JM, Bensinger SJ, Flavell RA. York AG, et al. Nature. 2024 Mar;627(8004):628-635. doi: 10.1038/s41586-024-07098-5. Epub 2024 Feb 21. Nature. 2024. PMID: 38383790 Free PMC article.
Mechanisms of action and resistance in histone methylation-targeted therapy.
Yamagishi M, Kuze Y, Kobayashi S, Nakashima M, Morishima S, Kawamata T, Makiyama J, Suzuki K, Seki M, Abe K, Imamura K, Watanabe E, Tsuchiya K, Yasumatsu I, Takayama G, Hizukuri Y, Ito K, Taira Y, Nannya Y, Tojo A, Watanabe T, Tsutsumi S, Suzuki Y, Uchimaru K. Yamagishi M, et al. Nature. 2024 Mar;627(8002):221-228. doi: 10.1038/s41586-024-07103-x. Epub 2024 Feb 21. Nature. 2024. PMID: 38383791 Free PMC article.
Backdoor.
Gento G. Gento G. Nature. 2024 Feb 21. doi: 10.1038/d41586-024-00336-w. Online ahead of print. Nature. 2024. PMID: 38383644 No abstract available.
Super-additive cooperation.
Efferson C, Bernhard H, Fischbacher U, Fehr E. Efferson C, et al. Nature. 2024 Feb;626(8001):1034-1041. doi: 10.1038/s41586-024-07077-w. Epub 2024 Feb 21. Nature. 2024. PMID: 38383778 Free PMC article.
The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons.
Makhlouf L, Peter JJ, Magnussen HM, Thakur R, Millrine D, Minshull TC, Harrison G, Varghese J, Lamoliatte F, Foglizzo M, Macartney T, Calabrese AN, Zeqiraj E, Kulathu Y. Makhlouf L, et al. Nature. 2024 Mar;627(8003):437-444. doi: 10.1038/s41586-024-07093-w. Epub 2024 Feb 21. Nature. 2024. PMID: 38383789 Free PMC article.
WNT signalling control by KDM5C during development affects cognition.
Karwacki-Neisius V, Jang A, Cukuroglu E, Tai A, Jiao A, Predes D, Yoon J, Brookes E, Chen J, Iberg A, Halbritter F, Õunap K, Gecz J, Schlaeger TM, Ho Sui S, Göke J, He X, Lehtinen MK, Pomeroy SL, Shi Y. Karwacki-Neisius V, et al. Nature. 2024 Mar;627(8004):594-603. doi: 10.1038/s41586-024-07067-y. Epub 2024 Feb 21. Nature. 2024. PMID: 38383780 Free PMC article.
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.
Afzali AM, Nirschl L, Sie C, Pfaller M, Ulianov O, Hassler T, Federle C, Petrozziello E, Kalluri SR, Chen HH, Tyystjärvi S, Muschaweckh A, Lammens K, Delbridge C, Büttner A, Steiger K, Seyhan G, Ottersen OP, Öllinger R, Rad R, Jarosch S, Straub A, Mühlbauer A, Grassmann S, Hemmer B, Böttcher JP, Wagner I, Kreutzfeldt M, Merkler D, Pardàs IB, Schmidt Supprian M, Buchholz VR, Heink S, Busch DH, Klein L, Korn T. Afzali AM, et al. Nature. 2024 Mar;627(8003):407-415. doi: 10.1038/s41586-024-07079-8. Epub 2024 Feb 21. Nature. 2024. PMID: 38383779 Free PMC article.
UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
DaRosa PA, Penchev I, Gumbin SC, Scavone F, Wąchalska M, Paulo JA, Ordureau A, Peter JJ, Kulathu Y, Harper JW, Becker T, Beckmann R, Kopito RR. DaRosa PA, et al. Nature. 2024 Mar;627(8003):445-452. doi: 10.1038/s41586-024-07073-0. Epub 2024 Feb 21. Nature. 2024. PMID: 38383785
47 results