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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
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259 results

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Page 1
Therapeutic Potential of Cannabis, Cannabidiol, and Cannabinoid-Based Pharmaceuticals.
Legare CA, Raup-Konsavage WM, Vrana KE. Legare CA, et al. Pharmacology. 2022;107(3-4):131-149. doi: 10.1159/000521683. Epub 2022 Jan 28. Pharmacology. 2022. PMID: 35093949 Free article. Review.
BACKGROUND: There is a growing interest in the use of cannabis (and its extracts), as well as CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is reason to believe that cannabinoids may be efficacious for a number of different diseases …
BACKGROUND: There is a growing interest in the use of cannabis (and its extracts), as well as CBD oil (hemp extracts containing cannabidi …
Constituents of Cannabis Sativa.
Rock EM, Parker LA. Rock EM, et al. Adv Exp Med Biol. 2021;1264:1-13. doi: 10.1007/978-3-030-57369-0_1. Adv Exp Med Biol. 2021. PMID: 33332000 Review.
There are more than 550 chemical compounds in cannabis, with more than 100 phytocannabinoids being identified, including delta(9)-tetrahydrocannabinol (THC) and cannabidiol (CBD). These phytocannabinoids work by binding to the cannabinoid receptors, as well as other recept …
There are more than 550 chemical compounds in cannabis, with more than 100 phytocannabinoids being identified, including delta(9)-tetrahydro …
Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies.
Solmi M, De Toffol M, Kim JY, Choi MJ, Stubbs B, Thompson T, Firth J, Miola A, Croatto G, Baggio F, Michelon S, Ballan L, Gerdle B, Monaco F, Simonato P, Scocco P, Ricca V, Castellini G, Fornaro M, Murru A, Vieta E, Fusar-Poli P, Barbui C, Ioannidis JPA, Carvalho AF, Radua J, Correll CU, Cortese S, Murray RM, Castle D, Shin JI, Dragioti E. Solmi M, et al. BMJ. 2023 Aug 30;382:e072348. doi: 10.1136/bmj-2022-072348. BMJ. 2023. PMID: 37648266 Free PMC article.
Cannabidiol improved 50% reduction of seizures (0.59 (0.38 to 0.92)) and seizure events (0.59 (0.36 to 0.96)) (GRADE=high), but increased pneumonia, gastrointestinal adverse events, and somnolence (GRADE=moderate). ...For multiple sclerosis, cannabinoids improved spasticit …
Cannabidiol improved 50% reduction of seizures (0.59 (0.38 to 0.92)) and seizure events (0.59 (0.36 to 0.96)) (GRADE=high), but incre …
Therapeutic Use of Cannabis and Cannabinoids: A Review.
Hsu M, Shah A, Jordan A, Gold MS, Hill KP. Hsu M, et al. JAMA. 2026 Jan 27;335(4):345-359. doi: 10.1001/jama.2025.19433. JAMA. 2026. PMID: 41296368 Review.
An estimated 10.5% of the US population reports using cannabidiol (CBD), a chemical compound extracted from cannabis that does not have psychoactive effects, for therapeutic purposes. OBSERVATIONS: Conditions for which cannabinoids have approval from the US Food and Drug A …
An estimated 10.5% of the US population reports using cannabidiol (CBD), a chemical compound extracted from cannabis that does not ha …
Cannabinoids: Therapeutic Use in Clinical Practice.
Pagano C, Navarra G, Coppola L, Avilia G, Bifulco M, Laezza C. Pagano C, et al. Int J Mol Sci. 2022 Mar 19;23(6):3344. doi: 10.3390/ijms23063344. Int J Mol Sci. 2022. PMID: 35328765 Free PMC article. Review.
Today, FDA-approved drugs, such as nabiximols (a mixture of THC and non-psychoactive cannabidiol (CBD)), are employed in alleviating pain and spasticity in multiple sclerosis. Dronabinol and nabilone are used for the treatment of chemotherapy-induced nausea and vomi …
Today, FDA-approved drugs, such as nabiximols (a mixture of THC and non-psychoactive cannabidiol (CBD)), are employed in alleviating …
Cannabis, cannabinoids and health: a review of evidence on risks and medical benefits.
Hoch E, Volkow ND, Friemel CM, Lorenzetti V, Freeman TP, Hall W. Hoch E, et al. Eur Arch Psychiatry Clin Neurosci. 2025 Mar;275(2):281-292. doi: 10.1007/s00406-024-01880-2. Epub 2024 Sep 19. Eur Arch Psychiatry Clin Neurosci. 2025. PMID: 39299947 Free PMC article. Review.
This is primarily the case in treating chronic pain, muscle spasticity, chemotherapy-induced nausea and vomiting, and refractory epilepsy (in the case of cannabidiol, CBD). The evidence is inconclusive on their value in treating mental disorders and other medical co …
This is primarily the case in treating chronic pain, muscle spasticity, chemotherapy-induced nausea and vomiting, and refractory epil …
Therapeutic Potential of Cannabidiol, Cannabidiolic Acid, and Cannabidiolic Acid Methyl Ester as Treatments for Nausea and Vomiting.
Rock EM, Limebeer CL, Pertwee RG, Mechoulam R, Parker LA. Rock EM, et al. Cannabis Cannabinoid Res. 2021 Aug;6(4):266-274. doi: 10.1089/can.2021.0041. Epub 2021 Jun 11. Cannabis Cannabinoid Res. 2021. PMID: 34115951 Free PMC article. Review.
With the currently available treatments, vomiting and especially nausea remain problematic, highlighting the need for alternative treatments. Discussion: Here we review in vitro and in vivo evidence for the effectiveness of the nonpsychoactive cannabinoid cannabidiol …
With the currently available treatments, vomiting and especially nausea remain problematic, highlighting the need for alternative tre …
Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indications.
Bilbao A, Spanagel R. Bilbao A, et al. BMC Med. 2022 Aug 19;20(1):259. doi: 10.1186/s12916-022-02459-1. BMC Med. 2022. PMID: 35982439 Free PMC article.
METHODS: We systematically reviewed (registered at PROSPERO: CRD42021229932) eight databases for randomized controlled trials (RCTs) of dronabinol, nabilone, cannabidiol and nabiximols for chronic pain, spasticity, nausea /vomiting, appetite, ALS, irritable bowel sy …
METHODS: We systematically reviewed (registered at PROSPERO: CRD42021229932) eight databases for randomized controlled trials (RCTs) of dron …
Cannabidiol Interferes with Establishment of delta(9)-Tetrahydrocannabinol-Induced Nausea Through a 5-HT(1A) Mechanism.
DeVuono MV, La Caprara O, Petrie GN, Limebeer CL, Rock EM, Hill MN, Parker LA. DeVuono MV, et al. Cannabis Cannabinoid Res. 2022 Feb;7(1):58-64. doi: 10.1089/can.2020.0083. Epub 2020 Dec 21. Cannabis Cannabinoid Res. 2022. PMID: 33998876 Free PMC article.
In this study, we evaluated if CBD would interfere with THC-induced nausea through a 5-HT(1A) receptor mechanism as it has been shown to interfere with nausea produced by lithium chloride (LiCl). ...Conclusions: CBD attenuated THC-induced nausea as well as TH …
In this study, we evaluated if CBD would interfere with THC-induced nausea through a 5-HT(1A) receptor mechanism as it has been shown …
Oral Cannabis Extract for Secondary Prevention of Chemotherapy-Induced Nausea and Vomiting: Final Results of a Randomized, Placebo-Controlled, Phase II/III Trial.
Grimison P, Mersiades A, Kirby A, Tognela A, Olver I, Morton RL, Haber P, Walsh A, Lee Y, Abdi E, Della-Fiorentina S, Aghmesheh M, Fox P, Briscoe K, Sanmugarajah J, Marx G, Kichenadasse G, Wheeler H, Chan M, Shannon J, Gedye C, Begbie S, Simes RJ, Stockler MR. Grimison P, et al. J Clin Oncol. 2024 Dec;42(34):4040-4050. doi: 10.1200/JCO.23.01836. Epub 2024 Aug 16. J Clin Oncol. 2024. PMID: 39151115 Free PMC article. Clinical Trial.
THC:CBD compared with placebo improved the complete response rate from 8% to 24% (absolute difference 16%, 95% CI, 4 to 28, P = .01), with similar effects for absence of significant nausea, use of rescue medications, daily vomits, and the nausea scale on the Functio …
THC:CBD compared with placebo improved the complete response rate from 8% to 24% (absolute difference 16%, 95% CI, 4 to 28, P = .01), with s …
259 results