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Accumulating postzygotic isolation genes in parapatry: a new twist on chromosomal speciation.
Navarro A, Barton NH. Navarro A, et al. Evolution. 2003 Mar;57(3):447-59. doi: 10.1111/j.0014-3820.2003.tb01537.x. Evolution. 2003. PMID: 12703935 Review.
Chromosomal rearrangements can promote reproductive isolation by reducing recombination along a large section of the genome. We model the effects of the genetic barrier to gene flow caused by a chromosomal rearrangement on the rate of accumulation of postzygotic iso …
Chromosomal rearrangements can promote reproductive isolation by reducing recombination along a large section of the genome. We model …
Chromosomal speciation and molecular divergence--accelerated evolution in rearranged chromosomes.
Navarro A, Barton NH. Navarro A, et al. Science. 2003 Apr 11;300(5617):321-4. doi: 10.1126/science.1080600. Science. 2003. PMID: 12690198
We analyzed human and chimpanzee sequence data to search for the patterns of divergence and polymorphism predicted by a theoretical model of speciation. ...
We analyzed human and chimpanzee sequence data to search for the patterns of divergence and polymorphism predicted by a theoretical m …
Positive selection in MAOA gene is human exclusive: determination of the putative amino acid change selected in the human lineage.
Andrés AM, Soldevila M, Navarro A, Kidd KK, Oliva B, Bertranpetit J. Andrés AM, et al. Hum Genet. 2004 Oct;115(5):377-86. doi: 10.1007/s00439-004-1179-6. Epub 2004 Sep 3. Hum Genet. 2004. PMID: 15349769
Among other activities, the gene has been shown to play a role in locomotion, circadian rhythm, and pain sensitivity and to have a critical influence on behavior and cognition. ...This human substitution affects protein dimerization according to a three-dimen …
Among other activities, the gene has been shown to play a role in locomotion, circadian rhythm, and pain sensitivity and to have a
Chromosomal rearrangements and the genomic distribution of gene-expression divergence in humans and chimpanzees.
Marquès-Bonet T, Cáceres M, Bertranpetit J, Preuss TM, Thomas JW, Navarro A. Marquès-Bonet T, et al. Trends Genet. 2004 Nov;20(11):524-9. doi: 10.1016/j.tig.2004.08.009. Trends Genet. 2004. PMID: 15475109
In addition, our results are consistent with a role for some rearrangements in the original speciation events that separated the human and chimpanzee lineages....
In addition, our results are consistent with a role for some rearrangements in the original speciation events that separated the huma …
Geographic stratification of linkage disequilibrium: a worldwide population study in a region of chromosome 22.
González-Neira A, Calafell F, Navarro A, Lao O, Cann H, Comas D, Bertranpetit J. González-Neira A, et al. Hum Genomics. 2004 Nov;1(6):399-409. doi: 10.1186/1479-7364-1-6-399. Hum Genomics. 2004. PMID: 15606995 Free PMC article.
Recent studies of haplotype diversity in a number of genomic regions have suggested that long stretches of DNA are preserved in the same chromosome, with little evidence of recombination events. The knowledge of the extent and strength of these haplotypes could become a
Recent studies of haplotype diversity in a number of genomic regions have suggested that long stretches of DNA are preserved in the s …
Chromosomal rearrangements are associated with higher rates of molecular evolution in mammals.
Marques-Bonet T, Navarro A. Marques-Bonet T, et al. Gene. 2005 Jul 4;353(2):147-54. doi: 10.1016/j.gene.2005.05.007. Gene. 2005. PMID: 15951139
Recent studies suggest a possible association between chromosomal rearrangements and regions of greater divergence, but evidence is limited and contradictory. Here, we test the hypothesis of a relationship between chromosomal rearrangements and higher rates of molec …
Recent studies suggest a possible association between chromosomal rearrangements and regions of greater divergence, but evidence is l …
Murine segmental duplications are hot spots for chromosome and gene evolution.
Armengol L, Marquès-Bonet T, Cheung J, Khaja R, González JR, Scherer SW, Navarro A, Estivill X. Armengol L, et al. Genomics. 2005 Dec;86(6):692-700. doi: 10.1016/j.ygeno.2005.08.008. Epub 2005 Oct 26. Genomics. 2005. PMID: 16256303
Mouse and rat genomic sequences permit us to obtain a global view of evolutionary rearrangements that have occurred between the two species and to define hallmarks that might underlie these events. We present a comparative study of the sequence assemblies of mouse a …
Mouse and rat genomic sequences permit us to obtain a global view of evolutionary rearrangements that have occurred between the two s …
The prion protein gene in humans revisited: lessons from a worldwide resequencing study.
Soldevila M, Andrés AM, Ramírez-Soriano A, Marquès-Bonet T, Calafell F, Navarro A, Bertranpetit J. Soldevila M, et al. Genome Res. 2006 Feb;16(2):231-9. doi: 10.1101/gr.4345506. Epub 2005 Dec 20. Genome Res. 2006. PMID: 16369046 Free PMC article.
A comparison of neutrality test statistics for PRNP with other human genes indicates that the signal of positive selection on PRNP is stronger than expected from a possible confounding genome-wide background signal of population expansion. ...Second, our results are
A comparison of neutrality test statistics for PRNP with other human genes indicates that the signal of positive selection on PRNP is
The portability of tagSNPs across populations: a worldwide survey.
González-Neira A, Ke X, Lao O, Calafell F, Navarro A, Comas D, Cann H, Bumpstead S, Ghori J, Hunt S, Deloukas P, Dunham I, Cardon LR, Bertranpetit J. González-Neira A, et al. Genome Res. 2006 Mar;16(3):323-30. doi: 10.1101/gr.4138406. Epub 2006 Feb 8. Genome Res. 2006. PMID: 16467560 Free PMC article.
Indeed, tagSNP portability is a challenge for the applicability of HapMap results. We analyzed 144 SNPs in a 1-Mb region of chromosome 22 in 1055 individuals from 38 worldwide populations, classified into seven continental groups. ...This high degree of portability …
Indeed, tagSNP portability is a challenge for the applicability of HapMap results. We analyzed 144 SNPs in a 1-Mb region of ch …
Patterns and rates of intron divergence between humans and chimpanzees.
Gazave E, Marqués-Bonet T, Fernando O, Charlesworth B, Navarro A. Gazave E, et al. Genome Biol. 2007;8(2):R21. doi: 10.1186/gb-2007-8-2-r21. Genome Biol. 2007. PMID: 17309804 Free PMC article.
Our main findings are as follows: there was a strong positive correlation between intron length and divergence; there was a strong negative correlation between intron length and GC content; and divergence rates vary along introns and depending on their ordinal posit …
Our main findings are as follows: there was a strong positive correlation between intron length and divergence; there was a st …
1,490 results
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