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Keynote review: the adipocyte as a drug discovery target.
Nawrocki AR, Scherer PE. Nawrocki AR, et al. Drug Discov Today. 2005 Sep 15;10(18):1219-30. doi: 10.1016/S1359-6446(05)03569-5. Drug Discov Today. 2005. PMID: 16213414 Review.
A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity.
Combs TP, Pajvani UB, Berg AH, Lin Y, Jelicks LA, Laplante M, Nawrocki AR, Rajala MW, Parlow AF, Cheeseboro L, Ding YY, Russell RG, Lindemann D, Hartley A, Baker GR, Obici S, Deshaies Y, Ludgate M, Rossetti L, Scherer PE. Combs TP, et al. Among authors: nawrocki ar. Endocrinology. 2004 Jan;145(1):367-83. doi: 10.1210/en.2003-1068. Epub 2003 Oct 23. Endocrinology. 2004. PMID: 14576179
The delicate balance between fat and muscle: adipokines in metabolic disease and musculoskeletal inflammation.
Nawrocki AR, Scherer PE. Nawrocki AR, et al. Curr Opin Pharmacol. 2004 Jun;4(3):281-9. doi: 10.1016/j.coph.2004.03.003. Curr Opin Pharmacol. 2004. PMID: 15140421 Review.
Proangiogenic contribution of adiponectin toward mammary tumor growth in vivo.
Landskroner-Eiger S, Qian B, Muise ES, Nawrocki AR, Berger JP, Fine EJ, Koba W, Deng Y, Pollard JW, Scherer PE. Landskroner-Eiger S, et al. Among authors: nawrocki ar. Clin Cancer Res. 2009 May 15;15(10):3265-76. doi: 10.1158/1078-0432.CCR-08-2649. Epub 2009 May 15. Clin Cancer Res. 2009. PMID: 19447867 Free PMC article.
Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists.
Nawrocki AR, Rajala MW, Tomas E, Pajvani UB, Saha AK, Trumbauer ME, Pang Z, Chen AS, Ruderman NB, Chen H, Rossetti L, Scherer PE. Nawrocki AR, et al. J Biol Chem. 2006 Feb 3;281(5):2654-60. doi: 10.1074/jbc.M505311200. Epub 2005 Dec 2. J Biol Chem. 2006. PMID: 16326714
Effects of peripherally administered neuromedin U on energy and glucose homeostasis.
Peier AM, Desai K, Hubert J, Du X, Yang L, Qian Y, Kosinski JR, Metzger JM, Pocai A, Nawrocki AR, Langdon RB, Marsh DJ. Peier AM, et al. Among authors: nawrocki ar. Endocrinology. 2011 Jul;152(7):2644-54. doi: 10.1210/en.2010-1463. Epub 2011 May 17. Endocrinology. 2011. PMID: 21586559
Lack of association between adiponectin levels and atherosclerosis in mice.
Nawrocki AR, Hofmann SM, Teupser D, Basford JE, Durand JL, Jelicks LA, Woo CW, Kuriakose G, Factor SM, Tanowitz HB, Hui DY, Tabas I, Scherer PE. Nawrocki AR, et al. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1159-65. doi: 10.1161/ATVBAHA.109.195826. Epub 2010 Mar 18. Arterioscler Thromb Vasc Biol. 2010. PMID: 20299691 Free PMC article.
Neurotensin Is Coexpressed, Coreleased, and Acts Together With GLP-1 and PYY in Enteroendocrine Control of Metabolism.
Grunddal KV, Ratner CF, Svendsen B, Sommer F, Engelstoft MS, Madsen AN, Pedersen J, Nøhr MK, Egerod KL, Nawrocki AR, Kowalski T, Howard AD, Poulsen SS, Offermanns S, Bäckhed F, Holst JJ, Holst B, Schwartz TW. Grunddal KV, et al. Among authors: nawrocki ar. Endocrinology. 2016 Jan;157(1):176-94. doi: 10.1210/en.2015-1600. Epub 2015 Oct 15. Endocrinology. 2016. PMID: 26469136
Gender differences in adiponectin modulation of cardiac remodeling in mice deficient in endothelial nitric oxide synthase.
Durand JL, Nawrocki AR, Scherer PE, Jelicks LA. Durand JL, et al. Among authors: nawrocki ar. J Cell Biochem. 2012 Oct;113(10):3276-87. doi: 10.1002/jcb.24206. J Cell Biochem. 2012. PMID: 22644792 Free PMC article.
Glucagon like receptor 1/ glucagon dual agonist acutely enhanced hepatic lipid clearance and suppressed de novo lipogenesis in mice.
More VR, Lao J, McLaren DG, Cumiskey AM, Murphy BA, Chen Y, Previs S, Stout S, Patel R, Satapati S, Li W, Kowalik E, Szeto D, Nawrocki A, Pocai A, Wang L, Carrington P. More VR, et al. Among authors: nawrocki a. PLoS One. 2017 Oct 24;12(10):e0186586. doi: 10.1371/journal.pone.0186586. eCollection 2017. PLoS One. 2017. PMID: 29065174 Free PMC article.
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