Neale G - Search Results

1

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.

Man SM, Karki R, Malireddi RK, Neale G, Vogel P, Yamamoto M, Lamkanfi M, Kanneganti TD. Man SM, et al. Among authors: neale g. Nat Immunol. 2015 May;16(5):467-75. doi: 10.1038/ni.3118. Epub 2015 Mar 16. Nat Immunol. 2015. PMID: 25774715 Free PMC article.

2

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.

Shi LZ, Wang R, Huang G, Vogel P, Neale G, Green DR, Chi H. Shi LZ, et al. Among authors: neale g. J Exp Med. 2011 Jul 4;208(7):1367-76. doi: 10.1084/jem.20110278. Epub 2011 Jun 27. J Exp Med. 2011. PMID: 21708926 Free PMC article.

3

The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function.

Yang K, Neale G, Green DR, He W, Chi H. Yang K, et al. Among authors: neale g. Nat Immunol. 2011 Jul 17;12(9):888-97. doi: 10.1038/ni.2068. Nat Immunol. 2011. PMID: 21765414 Free PMC article.

4

Inflammasome is a central player in the induction of obesity and insulin resistance.

Stienstra R, van Diepen JA, Tack CJ, Zaki MH, van de Veerdonk FL, Perera D, Neale GA, Hooiveld GJ, Hijmans A, Vroegrijk I, van den Berg S, Romijn J, Rensen PC, Joosten LA, Netea MG, Kanneganti TD. Stienstra R, et al. Among authors: neale ga. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15324-9. doi: 10.1073/pnas.1100255108. Epub 2011 Aug 29. Proc Natl Acad Sci U S A. 2011. PMID: 21876127 Free PMC article.

5

The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization.

Ippagunta SK, Malireddi RK, Shaw PJ, Neale GA, Vande Walle L, Green DR, Fukui Y, Lamkanfi M, Kanneganti TD. Ippagunta SK, et al. Nat Immunol. 2011 Sep 4;12(10):1010-6. doi: 10.1038/ni.2095. Nat Immunol. 2011. PMID: 21892172 Free PMC article.

6

Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function.

Wang Y, Huang G, Vogel P, Neale G, Reizis B, Chi H. Wang Y, et al. Among authors: neale g. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):E343-52. doi: 10.1073/pnas.1115635109. Epub 2012 Jan 23. Proc Natl Acad Sci U S A. 2012. PMID: 22308391 Free PMC article.

7

Abcb11 deficiency induces cholestasis coupled to impaired β-fatty acid oxidation in mice.

Zhang Y, Li F, Patterson AD, Wang Y, Krausz KW, Neale G, Thomas S, Nachagari D, Vogel P, Vore M, Gonzalez FJ, Schuetz JD. Zhang Y, et al. Among authors: neale g. J Biol Chem. 2012 Jul 13;287(29):24784-94. doi: 10.1074/jbc.M111.329318. Epub 2012 May 22. J Biol Chem. 2012. PMID: 22619174 Free PMC article.

8

Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines.

Ippagunta SK, Malireddi RK, Shaw PJ, Neale GA, Vande Walle L, Fukui Y, Green DR, Lamkanfi M, Kanneganti TD. Ippagunta SK, et al. Nat Immunol. 2012 Jul;13(7):701-2. doi: 10.1038/ni.2389. Nat Immunol. 2012. PMID: 22905357 No abstract available.

9

mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function.

Zeng H, Yang K, Cloer C, Neale G, Vogel P, Chi H. Zeng H, et al. Among authors: neale g. Nature. 2013 Jul 25;499(7459):485-90. doi: 10.1038/nature12297. Epub 2013 Jun 30. Nature. 2013. PMID: 23812589 Free PMC article.

10

T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming.

Yang K, Shrestha S, Zeng H, Karmaus PW, Neale G, Vogel P, Guertin DA, Lamb RF, Chi H. Yang K, et al. Among authors: neale g. Immunity. 2013 Dec 12;39(6):1043-56. doi: 10.1016/j.immuni.2013.09.015. Epub 2013 Dec 5. Immunity. 2013. PMID: 24315998 Free PMC article.

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