Neamati N - Search Results

1

Metal-dependent inhibition of HIV-1 integrase.

Neamati N, Lin Z, Karki RG, Orr A, Cowansage K, Strumberg D, Pais GC, Voigt JH, Nicklaus MC, Winslow HE, Zhao H, Turpin JA, Yi J, Skalka AM, Burke TR Jr, Pommier Y. Neamati N, et al. J Med Chem. 2002 Dec 19;45(26):5661-70. doi: 10.1021/jm0201417. J Med Chem. 2002. PMID: 12477350

We had previously identified a series of salicylhydrazides as potent inhibitors of IN in vitro (Neamati, N.; et al. J. Med. Chem. 1998, 41, 3202-3209.). Herein, we report the design, synthesis, and antiviral activity of three novel mercaptosalicylhydrazide (MSH) der …

We had previously identified a series of salicylhydrazides as potent inhibitors of IN in vitro (Neamati, N.; et al. J. Med. Ch …

2

Effects of nucleotide analogues on human immunodeficiency virus type 1 integrase.

Mazumder A, Neamati N, Sommadossi JP, Gosselin G, Schinazi RF, Imbach JL, Pommier Y. Mazumder A, et al. Among authors: neamati n. Mol Pharmacol. 1996 Apr;49(4):621-8. Mol Pharmacol. 1996. PMID: 8609889

3

Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease.

Mazumder A, Wang S, Neamati N, Nicklaus M, Sunder S, Chen J, Milne GW, Rice WG, Burke TR Jr, Pommier Y. Mazumder A, et al. Among authors: neamati n. J Med Chem. 1996 Jun 21;39(13):2472-81. doi: 10.1021/jm960074e. J Med Chem. 1996. PMID: 8691444

4

Inhibition of the human immunodeficiency virus type 1 integrase by guanosine quartet structures.

Mazumder A, Neamati N, Ojwang JO, Sunder S, Rando RF, Pommier Y. Mazumder A, et al. Among authors: neamati n. Biochemistry. 1996 Oct 29;35(43):13762-71. doi: 10.1021/bi960541u. Biochemistry. 1996. PMID: 8901518

5

Chemical trapping of ternary complexes of human immunodeficiency virus type 1 integrase, divalent metal, and DNA substrates containing an abasic site. Implications for the role of lysine 136 in DNA binding.

Mazumder A, Neamati N, Pilon AA, Sunder S, Pommier Y. Mazumder A, et al. Among authors: neamati n. J Biol Chem. 1996 Nov 1;271(44):27330-8. doi: 10.1074/jbc.271.44.27330. J Biol Chem. 1996. PMID: 8910309 Free article.

6

Coumarin-based inhibitors of HIV integrase.

Zhao H, Neamati N, Hong H, Mazumder A, Wang S, Sunder S, Milne GW, Pommier Y, Burke TR Jr. Zhao H, et al. Among authors: neamati n. J Med Chem. 1997 Jan 17;40(2):242-9. doi: 10.1021/jm960450v. J Med Chem. 1997. PMID: 9003523

7

Diarylsulfones, a novel class of human immunodeficiency virus type 1 integrase inhibitors.

Neamati N, Mazumder A, Zhao H, Sunder S, Burke TR Jr, Schultz RJ, Pommier Y. Neamati N, et al. Antimicrob Agents Chemother. 1997 Feb;41(2):385-93. doi: 10.1128/AAC.41.2.385. Antimicrob Agents Chemother. 1997. PMID: 9021196 Free PMC article.

8

HIV-1 integrase pharmacophore: discovery of inhibitors through three-dimensional database searching.

Nicklaus MC, Neamati N, Hong H, Mazumder A, Sunder S, Chen J, Milne GW, Pommier Y. Nicklaus MC, et al. Among authors: neamati n. J Med Chem. 1997 Mar 14;40(6):920-9. doi: 10.1021/jm960596u. J Med Chem. 1997. PMID: 9083480

9

Discovery of HIV-1 integrase inhibitors by pharmacophore searching.

Hong H, Neamati N, Wang S, Nicklaus MC, Mazumder A, Zhao H, Burke TR Jr, Pommier Y, Milne GW. Hong H, et al. Among authors: neamati n. J Med Chem. 1997 Mar 14;40(6):930-6. doi: 10.1021/jm960754h. J Med Chem. 1997. PMID: 9083481

10

Hydrazide-containing inhibitors of HIV-1 integrase.

Zhao H, Neamati N, Sunder S, Hong H, Wang S, Milne GW, Pommier Y, Burke TR Jr. Zhao H, et al. Among authors: neamati n. J Med Chem. 1997 Mar 14;40(6):937-41. doi: 10.1021/jm960755+. J Med Chem. 1997. PMID: 9083482

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