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A combination of neutral loss and targeted product ion scanning with two enzymatic digestions facilitates the comprehensive mapping of phosphorylation sites.
Casado-Vela J, Ruiz EJ, Nebreda AR, Casal JI. Casado-Vela J, et al. Among authors: nebreda ar. Proteomics. 2007 Aug;7(15):2522-9. doi: 10.1002/pmic.200700026. Proteomics. 2007. PMID: 17610206
p18(Hamlet) mediates different p53-dependent responses to DNA-damage inducing agents.
Lafarga V, Cuadrado A, Nebreda AR. Lafarga V, et al. Among authors: nebreda ar. Cell Cycle. 2007 Oct 1;6(19):2319-22. doi: 10.4161/cc.6.19.4741. Epub 2007 Jul 12. Cell Cycle. 2007. PMID: 17700068
A two-step inactivation mechanism of Myt1 ensures CDK1/cyclin B activation and meiosis I entry.
Ruiz EJ, Vilar M, Nebreda AR. Ruiz EJ, et al. Among authors: nebreda ar. Curr Biol. 2010 Apr 27;20(8):717-23. doi: 10.1016/j.cub.2010.02.050. Epub 2010 Apr 1. Curr Biol. 2010. PMID: 20362450
Cell cycle regulation of the mammalian CDK activator RINGO/Speedy A.
Dinarina A, Santamaria PG, Nebreda AR. Dinarina A, et al. Among authors: nebreda ar. FEBS Lett. 2009 Sep 3;583(17):2772-8. doi: 10.1016/j.febslet.2009.07.028. Epub 2009 Jul 19. FEBS Lett. 2009. PMID: 19622356
Meiotic inactivation of Xenopus Myt1 by CDK/XRINGO, but not CDK/cyclin, via site-specific phosphorylation.
Ruiz EJ, Hunt T, Nebreda AR. Ruiz EJ, et al. Among authors: nebreda ar. Mol Cell. 2008 Oct 24;32(2):210-20. doi: 10.1016/j.molcel.2008.08.029. Mol Cell. 2008. PMID: 18951089
Negative regulation of cell-cycle progression by RINGO/Speedy E.
Dinarina A, Ruiz EJ, O'Loghlen A, Mouron S, Perez L, Nebreda AR. Dinarina A, et al. Among authors: nebreda ar. Biochem J. 2008 Mar 15;410(3):535-42. doi: 10.1042/BJ20071453. Biochem J. 2008. PMID: 18072937
Regulation of Cdc25C activity during the meiotic G2/M transition.
Perdiguero E, Nebreda AR. Perdiguero E, et al. Among authors: nebreda ar. Cell Cycle. 2004 Jun;3(6):733-7. Epub 2004 Jun 8. Cell Cycle. 2004. PMID: 15136768 Review.
CDK activation by non-cyclin proteins.
Nebreda AR. Nebreda AR. Curr Opin Cell Biol. 2006 Apr;18(2):192-8. doi: 10.1016/j.ceb.2006.01.001. Epub 2006 Feb 17. Curr Opin Cell Biol. 2006. PMID: 16488127 Review.
UV-induced downregulation of the CDC25B protein in human cells.
Lemaire M, Ducommun B, Nebreda AR. Lemaire M, et al. Among authors: nebreda ar. FEBS Lett. 2010 Mar 19;584(6):1199-204. doi: 10.1016/j.febslet.2010.02.043. Epub 2010 Feb 19. FEBS Lett. 2010. PMID: 20176018
Proteomic analysis of p38alpha mitogen-activated protein kinase-regulated changes in membrane fractions of RAS-transformed fibroblasts.
Alfonso P, Dolado I, Swat A, Núñez A, Cuadrado A, Nebreda AR, Casal JI. Alfonso P, et al. Among authors: nebreda ar. Proteomics. 2006 Apr;6 Suppl 1:S262-71. doi: 10.1002/pmic.200500350. Proteomics. 2006. PMID: 16534743
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