Nechaev S - Search Results

1

Bidirectional Transcription Arises from Two Distinct Hubs of Transcription Factor Binding and Active Chromatin.

Scruggs BS, Gilchrist DA, Nechaev S, Muse GW, Burkholder A, Fargo DC, Adelman K. Scruggs BS, et al. Among authors: nechaev s. Mol Cell. 2015 Jun 18;58(6):1101-12. doi: 10.1016/j.molcel.2015.04.006. Epub 2015 May 28. Mol Cell. 2015. PMID: 26028540 Free PMC article.

2

Promoter-proximal Pol II: when stalling speeds things up.

Nechaev S, Adelman K. Nechaev S, et al. Cell Cycle. 2008 Jun 1;7(11):1539-44. doi: 10.4161/cc.7.11.6006. Epub 2008 Mar 27. Cell Cycle. 2008. PMID: 18469524 Review.

3

Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals.

Henriques T, Gilchrist DA, Nechaev S, Bern M, Muse GW, Burkholder A, Fargo DC, Adelman K. Henriques T, et al. Among authors: nechaev s. Mol Cell. 2013 Nov 21;52(4):517-28. doi: 10.1016/j.molcel.2013.10.001. Epub 2013 Oct 31. Mol Cell. 2013. PMID: 24184211 Free PMC article.

4

RNA polymerase is poised for activation across the genome.

Muse GW, Gilchrist DA, Nechaev S, Shah R, Parker JS, Grissom SF, Zeitlinger J, Adelman K. Muse GW, et al. Among authors: nechaev s. Nat Genet. 2007 Dec;39(12):1507-11. doi: 10.1038/ng.2007.21. Epub 2007 Nov 11. Nat Genet. 2007. PMID: 17994021 Free PMC article.

5

NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly.

Gilchrist DA, Nechaev S, Lee C, Ghosh SK, Collins JB, Li L, Gilmour DS, Adelman K. Gilchrist DA, et al. Among authors: nechaev s. Genes Dev. 2008 Jul 15;22(14):1921-33. doi: 10.1101/gad.1643208. Genes Dev. 2008. PMID: 18628398 Free PMC article.

6

Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling.

Adelman K, Kennedy MA, Nechaev S, Gilchrist DA, Muse GW, Chinenov Y, Rogatsky I. Adelman K, et al. Among authors: nechaev s. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18207-12. doi: 10.1073/pnas.0910177106. Epub 2009 Oct 9. Proc Natl Acad Sci U S A. 2009. PMID: 19820169 Free PMC article.

7

Global analysis of short RNAs reveals widespread promoter-proximal stalling and arrest of Pol II in Drosophila.

Nechaev S, Fargo DC, dos Santos G, Liu L, Gao Y, Adelman K. Nechaev S, et al. Science. 2010 Jan 15;327(5963):335-8. doi: 10.1126/science.1181421. Epub 2009 Dec 10. Science. 2010. PMID: 20007866 Free PMC article.

8

Pol II waiting in the starting gates: Regulating the transition from transcription initiation into productive elongation.

Nechaev S, Adelman K. Nechaev S, et al. Biochim Biophys Acta. 2011 Jan;1809(1):34-45. doi: 10.1016/j.bbagrm.2010.11.001. Epub 2010 Nov 13. Biochim Biophys Acta. 2011. PMID: 21081187 Free PMC article. Review.

9

The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing.

Etchegaray JP, Zhong L, Li C, Henriques T, Ablondi E, Nakadai T, Van Rechem C, Ferrer C, Ross KN, Choi JE, Samarakkody A, Ji F, Chang A, Sadreyev RI, Ramaswamy S, Nechaev S, Whetstine JR, Roeder RG, Adelman K, Goren A, Mostoslavsky R. Etchegaray JP, et al. Among authors: nechaev s. Mol Cell. 2019 Aug 22;75(4):683-699.e7. doi: 10.1016/j.molcel.2019.06.034. Epub 2019 Aug 6. Mol Cell. 2019. PMID: 31399344 Free PMC article.

10

Analysis of paired end Pol II ChIP-seq and short capped RNA-seq in MCF-7 cells.

Scheidegger A, Burkholder A, Abbas A, Zarns K, Samarakkody A, Nechaev S. Scheidegger A, et al. Among authors: nechaev s. Genom Data. 2015 Sep 1;5:263-267. doi: 10.1016/j.gdata.2015.06.021. Genom Data. 2015. PMID: 26229744 Free PMC article.

., Nnoli, O., Jokinen, B., Zarns, K., Kubat, B., Dhasarathy, A. and Nechaev, S. (2015) RNA polymerase II pausing can be retained or acquired during activation of genes involved in the epithelial to mesenchymal transition. ...

., Nnoli, O., Jokinen, B., Zarns, K., Kubat, B., Dhasarathy, A. and Nechaev, S. (2015) RNA polymerase II pausing can be retain …

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