Neckers L - Search Results

1

Inhibition of HSP 90 is associated with potent anti-tumor activity in Papillary Renal Cell Carcinoma.

Pahwa R, Dubhashi J, Singh A, Jailwala P, Lobanov A, Thomas CJ, Ceribelli M, Wilson K, Ricketts CJ, Vocke CD, Wells C, Bottaro DP, Linehan WM, Neckers L, Srinivasan R. Pahwa R, et al. Among authors: neckers l. J Exp Clin Cancer Res. 2022 Jun 27;41(1):208. doi: 10.1186/s13046-022-02416-z. J Exp Clin Cancer Res. 2022. PMID: 35754026 Free PMC article.

2

Taxol induction of p21WAF1 and p53 requires c-raf-1.

Blagosklonny MV, Schulte TW, Nguyen P, Mimnaugh EG, Trepel J, Neckers L. Blagosklonny MV, et al. Among authors: neckers l. Cancer Res. 1995 Oct 15;55(20):4623-6. Cancer Res. 1995. PMID: 7553639

3

Taxol-induced apoptosis and phosphorylation of Bcl-2 protein involves c-Raf-1 and represents a novel c-Raf-1 signal transduction pathway.

Blagosklonny MV, Schulte T, Nguyen P, Trepel J, Neckers LM. Blagosklonny MV, et al. Among authors: neckers lm. Cancer Res. 1996 Apr 15;56(8):1851-4. Cancer Res. 1996. PMID: 8620503

4

Genistein-stimulated adherence of prostate cancer cells is associated with the binding of focal adhesion kinase to beta-1-integrin.

Bergan R, Kyle E, Nguyen P, Trepel J, Ingui C, Neckers L. Bergan R, et al. Among authors: neckers l. Clin Exp Metastasis. 1996 Sep;14(4):389-98. doi: 10.1007/BF00123398. Clin Exp Metastasis. 1996. PMID: 8878413

5

Modulation of p53, ErbB1, ErbB2, and Raf-1 expression in lung cancer cells by depsipeptide FR901228.

Yu X, Guo ZS, Marcu MG, Neckers L, Nguyen DM, Chen GA, Schrump DS. Yu X, et al. Among authors: neckers l. J Natl Cancer Inst. 2002 Apr 3;94(7):504-13. doi: 10.1093/jnci/94.7.504. J Natl Cancer Inst. 2002. PMID: 11929951

6

The heat shock protein 90 inhibitor geldanamycin and the ErbB inhibitor ZD1839 promote rapid PP1 phosphatase-dependent inactivation of AKT in ErbB2 overexpressing breast cancer cells.

Xu W, Yuan X, Jung YJ, Yang Y, Basso A, Rosen N, Chung EJ, Trepel J, Neckers L. Xu W, et al. Among authors: neckers l. Cancer Res. 2003 Nov 15;63(22):7777-84. Cancer Res. 2003. PMID: 14633703

7

Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity.

Bisht KS, Bradbury CM, Mattson D, Kaushal A, Sowers A, Markovina S, Ortiz KL, Sieck LK, Isaacs JS, Brechbiel MW, Mitchell JB, Neckers LM, Gius D. Bisht KS, et al. Among authors: neckers lm. Cancer Res. 2003 Dec 15;63(24):8984-95. Cancer Res. 2003. PMID: 14695217

8

Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity.

Mimnaugh EG, Xu W, Vos M, Yuan X, Isaacs JS, Bisht KS, Gius D, Neckers L. Mimnaugh EG, et al. Among authors: neckers l. Mol Cancer Ther. 2004 May;3(5):551-66. Mol Cancer Ther. 2004. PMID: 15141013

9

Genetic basis of cancer of the kidney: disease-specific approaches to therapy.

Linehan WM, Vasselli J, Srinivasan R, Walther MM, Merino M, Choyke P, Vocke C, Schmidt L, Isaacs JS, Glenn G, Toro J, Zbar B, Bottaro D, Neckers L. Linehan WM, et al. Among authors: neckers l. Clin Cancer Res. 2004 Sep 15;10(18 Pt 2):6282S-9S. doi: 10.1158/1078-0432.CCR-050013. Clin Cancer Res. 2004. PMID: 15448018 Review.

10

Novel mutations in FH and expansion of the spectrum of phenotypes expressed in families with hereditary leiomyomatosis and renal cell cancer.

Wei MH, Toure O, Glenn GM, Pithukpakorn M, Neckers L, Stolle C, Choyke P, Grubb R, Middelton L, Turner ML, Walther MM, Merino MJ, Zbar B, Linehan WM, Toro JR. Wei MH, et al. Among authors: neckers l. J Med Genet. 2006 Jan;43(1):18-27. doi: 10.1136/jmg.2005.033506. Epub 2005 Jun 3. J Med Genet. 2006. PMID: 15937070 Free PMC article.

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