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Scavenger receptors in homeostasis and immunity.
Canton J, Neculai D, Grinstein S. Canton J, et al. Among authors: neculai d. Nat Rev Immunol. 2013 Sep;13(9):621-34. doi: 10.1038/nri3515. Epub 2013 Aug 9. Nat Rev Immunol. 2013. PMID: 23928573 Review.
CD36 and malaria: friends or foes? A decade of data provides some answers.
Cabrera A, Neculai D, Kain KC. Cabrera A, et al. Among authors: neculai d. Trends Parasitol. 2014 Sep;30(9):436-44. doi: 10.1016/ Epub 2014 Aug 8. Trends Parasitol. 2014. PMID: 25113859 Review.
Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36.
Neculai D, Schwake M, Ravichandran M, Zunke F, Collins RF, Peters J, Neculai M, Plumb J, Loppnau P, Pizarro JC, Seitova A, Trimble WS, Saftig P, Grinstein S, Dhe-Paganon S. Neculai D, et al. Among authors: neculai m. Nature. 2013 Dec 5;504(7478):172-6. doi: 10.1038/nature12684. Epub 2013 Oct 27. Nature. 2013. PMID: 24162852
Plasmodium falciparum-CD36 Structure-Function Relationships Defined by Ortholog Scanning Mutagenesis.
Cabrera A, Neculai D, Tran V, Lavstsen T, Turner L, Kain KC. Cabrera A, et al. Among authors: neculai d. J Infect Dis. 2019 Feb 23;219(6):945-954. doi: 10.1093/infdis/jiy607. J Infect Dis. 2019. PMID: 30335152 Free PMC article.
A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis.
Armstrong SM, Sugiyama MG, Fung KY, Gao Y, Wang C, Levy AS, Azizi P, Roufaiel M, Zhu SN, Neculai D, Yin C, Bolz SS, Seidah NG, Cybulsky MI, Heit B, Lee WL. Armstrong SM, et al. Among authors: neculai d. Cardiovasc Res. 2015 Nov 1;108(2):268-77. doi: 10.1093/cvr/cvv218. Epub 2015 Sep 2. Cardiovasc Res. 2015. PMID: 26334034 Free PMC article.
Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing.
Lee KP, Dey M, Neculai D, Cao C, Dever TE, Sicheri F. Lee KP, et al. Among authors: neculai d. Cell. 2008 Jan 11;132(1):89-100. doi: 10.1016/j.cell.2007.10.057. Cell. 2008. PMID: 18191223 Free PMC article.
A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Sheng Y, Hong JH, Doherty R, Srikumar T, Shloush J, Avvakumov GV, Walker JR, Xue S, Neculai D, Wan JW, Kim SK, Arrowsmith CH, Raught B, Dhe-Paganon S. Sheng Y, et al. Among authors: neculai d. Mol Cell Proteomics. 2012 Aug;11(8):329-41. doi: 10.1074/mcp.O111.013706. Epub 2012 Apr 10. Mol Cell Proteomics. 2012. PMID: 22496338 Free PMC article.
Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination.
Tang X, Orlicky S, Lin Z, Willems A, Neculai D, Ceccarelli D, Mercurio F, Shilton BH, Sicheri F, Tyers M. Tang X, et al. Among authors: neculai d. Cell. 2007 Jun 15;129(6):1165-76. doi: 10.1016/j.cell.2007.04.042. Cell. 2007. PMID: 17574027
WD40 repeat F box proteins, such as Cdc4 and beta-TrCP, contain a conserved dimerization motif called the D domain. Here, we report that the D domain protomers of yeast Cdc4 and human beta-TrCP form a superhelical homotypic dimer. Disruption of the D domain c …
WD40 repeat F box proteins, such as Cdc4 and beta-TrCP, contain a conserved dimerization motif called the D domain. Here, we report t …
Impaired Lysosomal Integral Membrane Protein 2-dependent Peroxiredoxin 6 Delivery to Lamellar Bodies Accounts for Altered Alveolar Phospholipid Content in Adaptor Protein-3-deficient pearl Mice.
Kook S, Wang P, Young LR, Schwake M, Saftig P, Weng X, Meng Y, Neculai D, Marks MS, Gonzales L, Beers MF, Guttentag S. Kook S, et al. Among authors: neculai d. J Biol Chem. 2016 Apr 15;291(16):8414-27. doi: 10.1074/jbc.M116.720201. Epub 2016 Feb 23. J Biol Chem. 2016. PMID: 26907692 Free PMC article.
Oligomerization-primed coiled-coil domain interaction with Ubc13 confers processivity to TRAF6 ubiquitin ligase activity.
Hu L, Xu J, Xie X, Zhou Y, Tao P, Li H, Han X, Wang C, Liu J, Xu P, Neculai D, Xia Z. Hu L, et al. Among authors: neculai d. Nat Commun. 2017 Oct 9;8(1):814. doi: 10.1038/s41467-017-01290-0. Nat Commun. 2017. PMID: 28993672 Free PMC article.
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