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Page 1
Vitamin D regulates microbiome-dependent cancer immunity.
Giampazolias E, Pereira da Costa M, Lam KC, Lim KHJ, Cardoso A, Piot C, Chakravarty P, Blasche S, Patel S, Biram A, Castro-Dopico T, Buck MD, Rodrigues RR, Poulsen GJ, Palma-Duran SA, Rogers NC, Koufaki MA, Minutti CM, Wang P, Vdovin A, Frederico B, Childs E, Lee S, Simpson B, Iseppon A, Omenetti S, Kelly G, Goldstone R, Nye E, Suárez-Bonnet A, Priestnall SL, MacRae JI, Zelenay S, Patil KR, Litchfield K, Lee JC, Jess T, Goldszmid RS, Reis e Sousa C. Giampazolias E, et al. Among authors: rogers nc. Science. 2024 Apr 26;384(6694):428-437. doi: 10.1126/science.adh7954. Epub 2024 Apr 25. Science. 2024. PMID: 38662827 Free PMC article.
Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity.
Giampazolias E, Schulz O, Lim KHJ, Rogers NC, Chakravarty P, Srinivasan N, Gordon O, Cardoso A, Buck MD, Poirier EZ, Canton J, Zelenay S, Sammicheli S, Moncaut N, Varsani-Brown S, Rosewell I, Reis e Sousa C. Giampazolias E, et al. Among authors: rogers nc. Cell. 2021 Jul 22;184(15):4016-4031.e22. doi: 10.1016/j.cell.2021.05.021. Epub 2021 Jun 2. Cell. 2021. PMID: 34081922 Free PMC article.
The receptor DNGR-1 signals for phagosomal rupture to promote cross-presentation of dead-cell-associated antigens.
Canton J, Blees H, Henry CM, Buck MD, Schulz O, Rogers NC, Childs E, Zelenay S, Rhys H, Domart MC, Collinson L, Alloatti A, Ellison CJ, Amigorena S, Papayannopoulos V, Thomas DC, Randow F, Reis e Sousa C. Canton J, et al. Among authors: rogers nc. Nat Immunol. 2021 Feb;22(2):140-153. doi: 10.1038/s41590-020-00824-x. Epub 2020 Dec 21. Nat Immunol. 2021. PMID: 33349708 Free PMC article.
SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells.
Henry CM, Castellanos CA, Buck MD, Giampazolias E, Frederico B, Cardoso A, Rogers NC, Schulz O, Lee S, Canton J, Faull P, Snijders AP, Mohapatra B, Band H, Reis e Sousa C. Henry CM, et al. Among authors: rogers nc. Cell Rep. 2023 Dec 26;42(12):113506. doi: 10.1016/j.celrep.2023.113506. Epub 2023 Nov 28. Cell Rep. 2023. PMID: 38019655 Free article.
DNGR-1 signalling limits dendritic cell activation for optimal antigen cross-presentation.
Buck MD, Castro-Dopico T, Schulz O, Cardoso A, Chakravarty P, Legrave N, Henry CM, Canton J, Wu E, Lee S, Rogers NC, Poirier EZ, Stainier W, Bosteels V, Childs E, MacRae JI, Skehel JM, Zelenay S, Reis E Sousa C. Buck MD, et al. Among authors: rogers nc. EMBO J. 2025 Dec;44(23):6857-6891. doi: 10.1038/s44318-025-00620-z. Epub 2025 Oct 29. EMBO J. 2025. PMID: 41162754 Free PMC article.
Cross-presentation of dead cell-associated antigens shapes the neoantigenic landscape of tumor immunity.
Lim KHJ, Schulz O, Lobon I, Castro-Dopico T, Zapata L, Giampazolias E, Frederico B, Castellanos CA, Buck MD, Stainier W, Chakravarty P, Kelly G, Rogers NC, Cardoso A, Lee S, Vash B, Maiocco S, Mehta R, Strid J, Turajlić S, Reis E Sousa C. Lim KHJ, et al. Among authors: rogers nc. Nat Immunol. 2026 Jan;27(1):72-81. doi: 10.1038/s41590-025-02354-w. Epub 2026 Jan 2. Nat Immunol. 2026. PMID: 41482545 Free PMC article.
Loss of secreted gelsolin enhances response to anticancer therapies.
Lim KHJ, Giampazolias E, Schulz O, Rogers NC, Wilkins A, Sahai E, Strid J, Reis e Sousa C. Lim KHJ, et al. Among authors: rogers nc. J Immunother Cancer. 2022 Sep;10(9):e005245. doi: 10.1136/jitc-2022-005245. J Immunother Cancer. 2022. PMID: 36162919 Free PMC article.
Interplay between CXCR4 and CCR2 regulates bone marrow exit of dendritic cell progenitors.
Pereira da Costa M, Minutti CM, Piot C, Giampazolias E, Cardoso A, Cabeza-Cabrerizo M, Rogers NC, Lebrusant-Fernandez M, Iliakis CS, Wack A, Reis e Sousa C. Pereira da Costa M, et al. Among authors: rogers nc. Cell Rep. 2023 Aug 29;42(8):112881. doi: 10.1016/j.celrep.2023.112881. Epub 2023 Jul 30. Cell Rep. 2023. PMID: 37523265 Free article.
25 results