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522 results

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Gemcitabine combined with docetaxel precisely regressed a recurrent leiomyosarcoma peritoneal metastasis in a patient-derived orthotopic xenograft (PDOX) model.
Miyake K, Kiyuna T, Miyake M, Kawaguchi K, Zhang Z, Wangsiricharoen S, Razmjooei S, Oshiro H, Higuchi T, Li Y, Nelson SD, Murakami T, Hiroshima Y, Kumamoto T, Matsuyama R, Bouvet M, Singh SR, Chawla SP, Endo I, Hoffman RM. Miyake K, et al. Among authors: nelson sd. Biochem Biophys Res Commun. 2019 Feb 19;509(4):1041-1046. doi: 10.1016/j.bbrc.2019.01.046. Epub 2019 Jan 16. Biochem Biophys Res Commun. 2019. PMID: 30660363
Ewing Sarcoma in a Patient With Cowden Syndrome.
Chandhanayingyong MC, Bernthal NM, Ungarreevittaya P, Nelson SD, Chawla SP, Singh AS. Chandhanayingyong MC, et al. Among authors: nelson sd. J Natl Compr Canc Netw. 2015 Nov;13(11):1310-4. doi: 10.6004/jnccn.2015.0161. J Natl Compr Canc Netw. 2015. PMID: 26553762
Vemurafenib-resistant BRAF-V600E-mutated melanoma is regressed by MEK-targeting drug trametinib, but not cobimetinib in a patient-derived orthotopic xenograft (PDOX) mouse model.
Kawaguchi K, Murakami T, Chmielowski B, Igarashi K, Kiyuna T, Unno M, Nelson SD, Russell TA, Dry SM, Li Y, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: nelson sd. Oncotarget. 2016 Nov 1;7(44):71737-71743. doi: 10.18632/oncotarget.12328. Oncotarget. 2016. PMID: 27690220 Free PMC article.
Patient-derived orthotopic xenograft (PDOX) mouse model of adult rhabdomyosarcoma invades and recurs after resection in contrast to the subcutaneous ectopic model.
Igarashi K, Kawaguchi K, Kiyuna T, Murakami T, Miwa S, Nelson SD, Dry SM, Li Y, Singh A, Kimura H, Hayashi K, Yamamoto N, Tsuchiya H, Eilber FC, Hoffman RM. Igarashi K, et al. Among authors: nelson sd. Cell Cycle. 2017 Jan 2;16(1):91-94. doi: 10.1080/15384101.2016.1252885. Epub 2016 Nov 10. Cell Cycle. 2017. PMID: 27830986 Free PMC article.
Tumor-targeting Salmonella typhimurium A1-R combined with temozolomide regresses malignant melanoma with a BRAF-V600E mutation in a patient-derived orthotopic xenograft (PDOX) model.
Kawaguchi K, Igarashi K, Murakami T, Chmielowski B, Kiyuna T, Zhao M, Zhang Y, Singh A, Unno M, Nelson SD, Russell TA, Dry SM, Li Y, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: nelson sd. Oncotarget. 2016 Dec 27;7(52):85929-85936. doi: 10.18632/oncotarget.13231. Oncotarget. 2016. PMID: 27835903 Free PMC article.
Tumor-targeting Salmonella typhimurium A1-R regresses an osteosarcoma in a patient-derived xenograft model resistant to a molecular-targeting drug.
Murakami T, Igarashi K, Kawaguchi K, Kiyuna T, Zhang Y, Zhao M, Hiroshima Y, Nelson SD, Dry SM, Li Y, Yanagawa J, Russell T, Federman N, Singh A, Elliott I, Matsuyama R, Chishima T, Tanaka K, Endo I, Eilber FC, Hoffman RM. Murakami T, et al. Among authors: nelson sd. Oncotarget. 2017 Jan 31;8(5):8035-8042. doi: 10.18632/oncotarget.14040. Oncotarget. 2017. PMID: 28030831 Free PMC article.
Tumor-Targeting Salmonella typhimurium A1-R Sensitizes Melanoma With a BRAF-V600E Mutation to Vemurafenib in a Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model.
Kawaguchi K, Igarashi K, Murakami T, Zhao M, Zhang Y, Chmielowski B, Kiyuna T, Nelson SD, Russell TA, Dry SM, Li Y, Unno M, Eilber FC, Hoffman RM. Kawaguchi K, et al. Among authors: nelson sd. J Cell Biochem. 2017 Aug;118(8):2314-2319. doi: 10.1002/jcb.25886. Epub 2017 Apr 25. J Cell Biochem. 2017. PMID: 28106277
High Efficacy of Pazopanib on an Undifferentiated Spindle-Cell Sarcoma Resistant to First-Line Therapy Is Identified With a Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model.
Igarashi K, Kawaguchi K, Murakami T, Kiyuna T, Miyake K, Singh AS, Nelson SD, Dry SM, Li Y, Yamamoto N, Hayashi K, Kimura H, Miwa S, Tsuchiya H, Eilber FC, Hoffman RM. Igarashi K, et al. Among authors: nelson sd. J Cell Biochem. 2017 Sep;118(9):2739-2743. doi: 10.1002/jcb.25923. Epub 2017 Apr 25. J Cell Biochem. 2017. PMID: 28176365
The irony of highly-effective bacterial therapy of a patient-derived orthotopic xenograft (PDOX) model of Ewing's sarcoma, which was blocked by Ewing himself 80 years ago.
Murakami T, Kiyuna T, Kawaguchi K, Igarashi K, Singh AS, Hiroshima Y, Zhang Y, Zhao M, Miyake K, Nelson SD, Dry SM, Li Y, DeLong JC, Lwin TM, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM. Murakami T, et al. Among authors: nelson sd. Cell Cycle. 2017 Jun 3;16(11):1046-1052. doi: 10.1080/15384101.2017.1304340. Epub 2017 Mar 15. Cell Cycle. 2017. PMID: 28296559 Free PMC article.
Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.
Murakami T, Li S, Han Q, Tan Y, Kiyuna T, Igarashi K, Kawaguchi K, Hwang HK, Miyake K, Singh AS, Nelson SD, Dry SM, Li Y, Hiroshima Y, Lwin TM, DeLong JC, Chishima T, Tanaka K, Bouvet M, Endo I, Eilber FC, Hoffman RM. Murakami T, et al. Among authors: nelson sd. Oncotarget. 2017 May 30;8(22):35630-35638. doi: 10.18632/oncotarget.15823. Oncotarget. 2017. PMID: 28404944 Free PMC article.
522 results