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Surfactant in respiratory distress syndrome and lung injury.
Hallman M, Glumoff V, Rämet M. Hallman M, et al. Comp Biochem Physiol A Mol Integr Physiol. 2001 May;129(1):287-94. doi: 10.1016/s1095-6433(01)00324-5. Comp Biochem Physiol A Mol Integr Physiol. 2001. PMID: 11369552 Review.
A deficiency in alveolar surfactant due to immaturity of alveolar type II epithelial cells causes respiratory distress syndrome (RDS). ...Abnormalities in alveolar or airway surfactant characterize many lung and airway diseases. In the acute respira …
A deficiency in alveolar surfactant due to immaturity of alveolar type II epithelial cells causes respiratory distress …
Principles of surfactant replacement.
Robertson B, Halliday HL. Robertson B, et al. Biochim Biophys Acta. 1998 Nov 19;1408(2-3):346-61. doi: 10.1016/s0925-4439(98)00080-5. Biochim Biophys Acta. 1998. PMID: 9813384 Free article. Review.
Surfactant therapy is an established part of routine clinical management of babies with respiratory distress syndrome. An initial dose of about 100 mg/kg is usually needed to compensate for the well documented deficiency of alveolar surfactant in these babies …
Surfactant therapy is an established part of routine clinical management of babies with respiratory distress syndrome. An init …
Genetic basis of respiratory distress syndrome.
Hallman M, Haataja R. Hallman M, et al. Front Biosci. 2007 Jan 1;12:2670-82. doi: 10.2741/2263. Front Biosci. 2007. PMID: 17127271 Review.
The allelic variants of the genes encoding the surfactant proteins (SP) SP-A1, SP-A2, SP-B, and SP-C have been associated with RDS. The main SP-A haplotype, interactively with the SP-B Ile131Thr polymorphism and with …
The allelic variants of the genes encoding the surfactant proteins (SP) SP-A1, SP-A2, SP-B, and SP …
The Role of Surfactant in Lung Disease and Host Defense against Pulmonary Infections.
Han S, Mallampalli RK. Han S, et al. Ann Am Thorac Soc. 2015 May;12(5):765-74. doi: 10.1513/AnnalsATS.201411-507FR. Ann Am Thorac Soc. 2015. PMID: 25742123 Free PMC article. Review.
Surfactant is enriched with a relatively unique phospholipid, termed dipalmitoylphosphatidylcholine, and four surfactant-associated proteins, SP-A, SP-B, SP-C, and SP-D. The hydrophobic proteins, SP-B and SP-C, together with …
Surfactant is enriched with a relatively unique phospholipid, termed dipalmitoylphosphatidylcholine, and four surfactant-associated proteins …