Neschen S - Search Results

1

Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle.

Kim JK, Michael MD, Previs SF, Peroni OD, Mauvais-Jarvis F, Neschen S, Kahn BB, Kahn CR, Shulman GI. Kim JK, et al. Among authors: neschen s. J Clin Invest. 2000 Jun;105(12):1791-7. doi: 10.1172/JCI8305. J Clin Invest. 2000. PMID: 10862794 Free PMC article.

2

Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

Morino K, Petersen KF, Dufour S, Befroy D, Frattini J, Shatzkes N, Neschen S, White MF, Bilz S, Sono S, Pypaert M, Shulman GI. Morino K, et al. Among authors: neschen s. J Clin Invest. 2005 Dec;115(12):3587-93. doi: 10.1172/JCI25151. Epub 2005 Nov 10. J Clin Invest. 2005. PMID: 16284649 Free PMC article.

3

Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice.

Neschen S, Morino K, Hammond LE, Zhang D, Liu ZX, Romanelli AJ, Cline GW, Pongratz RL, Zhang XM, Choi CS, Coleman RA, Shulman GI. Neschen S, et al. Cell Metab. 2005 Jul;2(1):55-65. doi: 10.1016/j.cmet.2005.06.006. Cell Metab. 2005. PMID: 16054099 Free article.

4

Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-gamma-dependent mechanism in mice.

Neschen S, Morino K, Rossbacher JC, Pongratz RL, Cline GW, Sono S, Gillum M, Shulman GI. Neschen S, et al. Diabetes. 2006 Apr;55(4):924-8. doi: 10.2337/diabetes.55.04.06.db05-0985. Diabetes. 2006. PMID: 16567512

5

Muscle-specific IRS-1 Ser->Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle.

Morino K, Neschen S, Bilz S, Sono S, Tsirigotis D, Reznick RM, Moore I, Nagai Y, Samuel V, Sebastian D, White M, Philbrick W, Shulman GI. Morino K, et al. Among authors: neschen s. Diabetes. 2008 Oct;57(10):2644-51. doi: 10.2337/db06-0454. Epub 2008 Jul 15. Diabetes. 2008. PMID: 18633112 Free PMC article.

6

Resistance to high-fat diet-induced obesity and insulin resistance in mice with very long-chain acyl-CoA dehydrogenase deficiency.

Zhang D, Christianson J, Liu ZX, Tian L, Choi CS, Neschen S, Dong J, Wood PA, Shulman GI. Zhang D, et al. Among authors: neschen s. Cell Metab. 2010 May 5;11(5):402-11. doi: 10.1016/j.cmet.2010.03.012. Cell Metab. 2010. PMID: 20444420 Free PMC article.

7

Contrasting effects of fish oil and safflower oil on hepatic peroxisomal and tissue lipid content.

Neschen S, Moore I, Regittnig W, Yu CL, Wang Y, Pypaert M, Petersen KF, Shulman GI. Neschen S, et al. Am J Physiol Endocrinol Metab. 2002 Feb;282(2):E395-401. doi: 10.1152/ajpendo.00414.2001. Am J Physiol Endocrinol Metab. 2002. PMID: 11788372 Free PMC article.

8

Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation.

Gao Q, Wolfgang MJ, Neschen S, Morino K, Horvath TL, Shulman GI, Fu XY. Gao Q, et al. Among authors: neschen s. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4661-6. doi: 10.1073/pnas.0303992101. Epub 2004 Mar 22. Proc Natl Acad Sci U S A. 2004. PMID: 15070774 Free PMC article.

9

n-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-alpha-dependent manner.

Neschen S, Morino K, Dong J, Wang-Fischer Y, Cline GW, Romanelli AJ, Rossbacher JC, Moore IK, Regittnig W, Munoz DS, Kim JH, Shulman GI. Neschen S, et al. Diabetes. 2007 Apr;56(4):1034-41. doi: 10.2337/db06-1206. Epub 2007 Jan 24. Diabetes. 2007. PMID: 17251275

10

Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance.

Choi CS, Savage DB, Kulkarni A, Yu XX, Liu ZX, Morino K, Kim S, Distefano A, Samuel VT, Neschen S, Zhang D, Wang A, Zhang XM, Kahn M, Cline GW, Pandey SK, Geisler JG, Bhanot S, Monia BP, Shulman GI. Choi CS, et al. Among authors: neschen s. J Biol Chem. 2007 Aug 3;282(31):22678-88. doi: 10.1074/jbc.M704213200. Epub 2007 May 27. J Biol Chem. 2007. PMID: 17526931 Free article.

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