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Antagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formation.
Neubüser A, Peters H, Balling R, Martin GR. Neubüser A, et al. Cell. 1997 Jul 25;90(2):247-55. doi: 10.1016/s0092-8674(00)80333-5. Cell. 1997. PMID: 9244299
Thus it appears that the position of the teeth is determined by a combination of two different types of signaling molecules produced in wide but overlapping domains rather than by a single localized inducer. We suggest that a similar mechanism may be used for …
Thus it appears that the position of the teeth is determined by a combination of two different types of signaling molecules produced …
Expression and regulation of ANTXR1 in the chick embryo.
Herrmann D, Ferrer-Vaquer A, Lahsnig C, Firnberg N, Leibbrandt A, Neubüser A. Herrmann D, et al. Among authors: neubuser a. Dev Dyn. 2010 Feb;239(2):680-7. doi: 10.1002/dvdy.22194. Dev Dyn. 2010. PMID: 20034073 Free article.
FGF signaling regulates expression of Tbx2, Erm, Pea3, and Pax3 in the early nasal region.
Firnberg N, Neubüser A. Firnberg N, et al. Among authors: neubuser a. Dev Biol. 2002 Jul 15;247(2):237-50. doi: 10.1006/dbio.2002.0696. Dev Biol. 2002. PMID: 12086464
Here, we have used a candidate approach to identify genes that are induced in chick nasal mesenchyme in response to FGF signaling. Using an explant culture system, we show that expression of the transcription factors Tbx2, Erm, Pea3, and Pax3, but not Pax7, in nasal mesenc …
Here, we have used a candidate approach to identify genes that are induced in chick nasal mesenchyme in response to FGF signaling. Us …
Regulation of Tbx22 during facial and palatal development.
Fuchs A, Inthal A, Herrmann D, Cheng S, Nakatomi M, Peters H, Neubüser A. Fuchs A, et al. Among authors: neubuser a. Dev Dyn. 2010 Nov;239(11):2860-74. doi: 10.1002/dvdy.22421. Dev Dyn. 2010. PMID: 20845426 Free article.
Expression and regulation of HTRA1 during chick and early mouse development.
Ferrer-Vaquer A, Maurey P, Werzowa J, Firnberg N, Leibbrandt A, Neubüser A. Ferrer-Vaquer A, et al. Among authors: neubuser a. Dev Dyn. 2008 Jul;237(7):1893-900. doi: 10.1002/dvdy.21597. Dev Dyn. 2008. PMID: 18570253 Free article.
Expression of ASK1 during chick and early mouse development.
Ferrer-Vaquer A, Maurey P, Firnberg N, Leibbrandt A, Neubüser A. Ferrer-Vaquer A, et al. Among authors: neubuser a. Gene Expr Patterns. 2007 Aug;7(7):808-16. doi: 10.1016/j.modgep.2007.05.001. Epub 2007 May 24. Gene Expr Patterns. 2007. PMID: 17602894
Mesenchymal patterning by Hoxa2 requires blocking Fgf-dependent activation of Ptx1.
Bobola N, Carapuço M, Ohnemus S, Kanzler B, Leibbrandt A, Neubüser A, Drouin J, Mallo M. Bobola N, et al. Among authors: neubuser a. Development. 2003 Aug;130(15):3403-14. doi: 10.1242/dev.00554. Development. 2003. PMID: 12810588
Using a subtraction approach, we found that Ptx1 was upregulated in the second arch mesenchyme of Hoxa2 mutants. This upregulation has functional significance because, in Hoxa2(-/-);Ptx1(-/-) embryos, the Hoxa2(-/-) phenotype is partially reversed. ...Our findings have imp …
Using a subtraction approach, we found that Ptx1 was upregulated in the second arch mesenchyme of Hoxa2 mutants. This upregulation ha …
FGF signaling is required for initiation of feather placode development.
Mandler M, Neubüser A. Mandler M, et al. Among authors: neubuser a. Development. 2004 Jul;131(14):3333-43. doi: 10.1242/dev.01203. Epub 2004 Jun 16. Development. 2004. PMID: 15201222 Free article.
Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed.
Minowada G, Jarvis LA, Chi CL, Neubüser A, Sun X, Hacohen N, Krasnow MA, Martin GR. Minowada G, et al. Among authors: neubuser a. Development. 1999 Oct;126(20):4465-75. Development. 1999. PMID: 10498682
Here we describe a family of vertebrate Sprouty homologs and demonstrate that the regulatory relationship with FGF pathways has been conserved. ...Sprouty overexpression obtained by infecting the prospective wing territory of the chick embryo with a retrovirus conta …
Here we describe a family of vertebrate Sprouty homologs and demonstrate that the regulatory relationship with FGF pathways has been …
Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development.
Sander M, Neubüser A, Kalamaras J, Ee HC, Martin GR, German MS. Sander M, et al. Among authors: neubuser a. Genes Dev. 1997 Jul 1;11(13):1662-73. doi: 10.1101/gad.11.13.1662. Genes Dev. 1997. PMID: 9224716
We present genetic and biochemical evidence that PAX6 is a key regulator of pancreatic islet hormone gene transcription and is required for normal islet development. ...These effects appear to result from a lack of PAX6 protein in the mutant embryos. Biochemical stu …
We present genetic and biochemical evidence that PAX6 is a key regulator of pancreatic islet hormone gene transcription and is requir …
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