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Cytoplasmic activation-induced cytidine deaminase (AID) exists in stoichiometric complex with translation elongation factor 1α (eEF1A).
Häsler J, Rada C, Neuberger MS. Häsler J, et al. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18366-71. doi: 10.1073/pnas.1106729108. Epub 2011 Oct 31. Proc Natl Acad Sci U S A. 2011. PMID: 22042842 Free PMC article.
Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation.
Dingler FA, Kemmerich K, Neuberger MS, Rada C. Dingler FA, et al. Among authors: neuberger ms. Eur J Immunol. 2014 Jul;44(7):1925-35. doi: 10.1002/eji.201444482. Epub 2014 May 27. Eur J Immunol. 2014. PMID: 24771041 Free PMC article.
Structural and mutational analysis reveals that CTNNBL1 binds NLSs in a manner distinct from that of its closest armadillo-relative, karyopherin α.
Ganesh K, van Maldegem F, Telerman SB, Simpson P, Johnson CM, Williams RL, Neuberger MS, Rada C. Ganesh K, et al. Among authors: neuberger ms. FEBS Lett. 2014 Jan 3;588(1):21-7. doi: 10.1016/j.febslet.2013.11.013. Epub 2013 Nov 20. FEBS Lett. 2014. PMID: 24269683 Free PMC article.
Deficiency in spliceosome-associated factor CTNNBL1 does not affect ongoing cell cycling but delays exit from quiescence and results in embryonic lethality in mice.
Chandra A, van Maldegem F, Andrews S, Neuberger MS, Rada C. Chandra A, et al. Among authors: neuberger ms. Cell Cycle. 2013 Mar 1;12(5):732-42. doi: 10.4161/cc.23594. Epub 2013 Jan 23. Cell Cycle. 2013. PMID: 23343763 Free PMC article.
Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice.
Kemmerich K, Dingler FA, Rada C, Neuberger MS. Kemmerich K, et al. Among authors: neuberger ms. Nucleic Acids Res. 2012 Jul;40(13):6016-25. doi: 10.1093/nar/gks259. Epub 2012 Mar 24. Nucleic Acids Res. 2012. PMID: 22447450 Free PMC article.
REG-γ associates with and modulates the abundance of nuclear activation-induced deaminase.
Uchimura Y, Barton LF, Rada C, Neuberger MS. Uchimura Y, et al. Among authors: neuberger ms. J Exp Med. 2011 Nov 21;208(12):2385-91. doi: 10.1084/jem.20110856. Epub 2011 Oct 31. J Exp Med. 2011. PMID: 22042974 Free PMC article.
The cytoplasmic AID complex.
Häsler J, Rada C, Neuberger MS. Häsler J, et al. Among authors: neuberger ms. Semin Immunol. 2012 Aug;24(4):273-80. doi: 10.1016/j.smim.2012.05.004. Epub 2012 Jun 13. Semin Immunol. 2012. PMID: 22698843 Review.
The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence.
Geisberger R, Rada C, Neuberger MS. Geisberger R, et al. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6736-41. doi: 10.1073/pnas.0810808106. Epub 2009 Apr 7. Proc Natl Acad Sci U S A. 2009. PMID: 19351893 Free PMC article.
DNA deamination in immunity: AID in the context of its APOBEC relatives.
Conticello SG, Langlois MA, Yang Z, Neuberger MS. Conticello SG, et al. Adv Immunol. 2007;94:37-73. doi: 10.1016/S0065-2776(06)94002-4. Adv Immunol. 2007. PMID: 17560271 Review.
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