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Year Number of Results
2002 2
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Page 1
Cerebral Iron Deposition in Neurodegeneration.
Dusek P, Hofer T, Alexander J, Roos PM, Aaseth JO. Dusek P, et al. Biomolecules. 2022 May 17;12(5):714. doi: 10.3390/biom12050714. Biomolecules. 2022. PMID: 35625641 Free PMC article. Review.
On the microscopic level, brain iron deposits are present mostly in dystrophic microglia variably accompanied by iron-laden macrophages and in astrocytes, implicating a role of inflammatory changes and blood-brain barrier disturbance in iron
On the microscopic level, brain iron deposits are present mostly in dystrophic microglia variably accompanied by iron-l …
Brain iron transport.
Qian ZM, Ke Y. Qian ZM, et al. Biol Rev Camb Philos Soc. 2019 Oct;94(5):1672-1684. doi: 10.1111/brv.12521. Epub 2019 Jun 12. Biol Rev Camb Philos Soc. 2019. PMID: 31190441 Review.
Brain iron is a crucial participant and regulator of normal physiological activity. ...Abnormally high brain iron levels have been observed in various neurodegenerative diseases, including neurodegeneration with brain iron accum
Brain iron is a crucial participant and regulator of normal physiological activity. ...Abnormally high brain iron
Nomenclature of Genetic Movement Disorders: Recommendations of the International Parkinson and Movement Disorder Society Task Force - An Update.
Lange LM, Gonzalez-Latapi P, Rajalingam R, Tijssen MAJ, Ebrahimi-Fakhari D, Gabbert C, Ganos C, Ghosh R, Kumar KR, Lang AE, Rossi M, van der Veen S, van de Warrenburg B, Warner T, Lohmann K, Klein C, Marras C; on behalf of the Task Force on Genetic Nomenclature in Movement Disorders. Lange LM, et al. Mov Disord. 2022 May;37(5):905-935. doi: 10.1002/mds.28982. Epub 2022 Apr 28. Mov Disord. 2022. PMID: 35481685 Review.
In addition, with this update, we further refined the system and propose dissolving the imaging-based categories of Primary Familial Brain Calcification and Neurodegeneration with Brain Iron Accumulation and reclassifying these genetic condition …
In addition, with this update, we further refined the system and propose dissolving the imaging-based categories of Primary Familial Brai
Ferroptosis in Neurological Disease.
David S, Ryan F, Jhelum P, Kroner A. David S, et al. Neuroscientist. 2023 Oct;29(5):591-615. doi: 10.1177/10738584221100183. Epub 2022 Jun 8. Neuroscientist. 2023. PMID: 35678019 Review.
Iron accumulation in the CNS occurs in many neurological disorders. It can contribute to neuropathology as iron is a redox-active metal that can generate free radicals. The reasons for the iron buildup in these conditions are varied and depend on which
Iron accumulation in the CNS occurs in many neurological disorders. It can contribute to neuropathology as iron is a re
Neurodegeneration with brain iron accumulation.
Gregory A, Hayflick SJ. Gregory A, et al. Folia Neuropathol. 2005;43(4):286-96. Folia Neuropathol. 2005. PMID: 16416393 Free PMC article. Review.
Neurodegeneration with brain iron accumulation (NBIA) describes a group of progressive extrapyramidal disorders with radiographic evidence of focal iron accumulation in the brain, usually in the basal ganglia. ...In addition, a spe
Neurodegeneration with brain iron accumulation (NBIA) describes a group of progressive extrapyramidal disorders
Childhood disorders of neurodegeneration with brain iron accumulation (NBIA).
Kurian MA, McNeill A, Lin JP, Maher ER. Kurian MA, et al. Dev Med Child Neurol. 2011 May;53(5):394-404. doi: 10.1111/j.1469-8749.2011.03955.x. Dev Med Child Neurol. 2011. PMID: 21480873 Free article. Review.
Neurodegeneration with brain iron accumulation (NBIA) comprises a heterogeneous group of progressive complex motor disorders characterized by the presence of high brain iron, particularly within the basal ganglia. A number of autosomal re
Neurodegeneration with brain iron accumulation (NBIA) comprises a heterogeneous group of progressive complex mot
Oxidative stress and neurodegeneration: the involvement of iron.
Carocci A, Catalano A, Sinicropi MS, Genchi G. Carocci A, et al. Biometals. 2018 Oct;31(5):715-735. doi: 10.1007/s10534-018-0126-2. Epub 2018 Jul 16. Biometals. 2018. PMID: 30014355 Review.
Its accumulation in specific regions is associated with pathogenesis in a variety of neurodegenerative diseases (i.e., Parkinson's disease, Alzheimer's disease, Huntington's chorea, Amyotrophic Lateral Sclerosis and Neurodegeneration with Brain Iron
Its accumulation in specific regions is associated with pathogenesis in a variety of neurodegenerative diseases (i.e., Parkinson's di …
Pallidal degenerations and related disorders: an update.
Jellinger KA. Jellinger KA. J Neural Transm (Vienna). 2022 Jun;129(5-6):521-543. doi: 10.1007/s00702-021-02392-2. Epub 2021 Aug 7. J Neural Transm (Vienna). 2022. PMID: 34363531 Review.
One of the latter, and both PPND and DRPLA are particular subcortical 4-R tauopathies, related to progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) and frontotemporal lobe degeneration-17 (FTLD-17), while others show additional 3-R and 4-R tauopa …
One of the latter, and both PPND and DRPLA are particular subcortical 4-R tauopathies, related to progressive supranuclear palsy (PSP), cort …
Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury.
Farina M, Avila DS, da Rocha JB, Aschner M. Farina M, et al. Neurochem Int. 2013 Apr;62(5):575-94. doi: 10.1016/j.neuint.2012.12.006. Epub 2012 Dec 21. Neurochem Int. 2013. PMID: 23266600 Free PMC article. Review.
Among the 23 elements that have known physiological functions in humans, 12 are metals, including iron (Fe) and manganese (Mn). Nevertheless, excessive exposure to these metals may lead to pathological conditions, including neurodegeneration. ...Finally, we address …
Among the 23 elements that have known physiological functions in humans, 12 are metals, including iron (Fe) and manganese (Mn). Never …
Monoamine oxidase inhibitors, and iron chelators in depressive illness and neurodegenerative diseases.
Youdim MBH. Youdim MBH. J Neural Transm (Vienna). 2018 Nov;125(11):1719-1733. doi: 10.1007/s00702-018-1942-9. Epub 2018 Oct 19. J Neural Transm (Vienna). 2018. PMID: 30341696 Review.
Subsequent molecular pharmacological have also generated the concept of neuroprotection, reflecting the possibility of slowing, halting and maybe reversing, neurodegeneration in Parkinson's or Alzheimer's diseases. Increased levels of oxidative stress through the accumu
Subsequent molecular pharmacological have also generated the concept of neuroprotection, reflecting the possibility of slowing, halting and …
31 results