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113 results
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Ciprofloxacin greatly increases concentrations and hypotensive effect of tizanidine by inhibiting its cytochrome P450 1A2-mediated presystemic metabolism.
Granfors MT, Backman JT, Neuvonen M, Neuvonen PJ. Granfors MT, et al. Among authors: neuvonen pj, neuvonen m. Clin Pharmacol Ther. 2004 Dec;76(6):598-606. doi: 10.1016/j.clpt.2004.08.018. Clin Pharmacol Ther. 2004. PMID: 15592331 Clinical Trial.
Rifampin decreases the plasma concentrations and effects of repaglinide.
Niemi M, Backman JT, Neuvonen M, Neuvonen PJ, Kivistö KT. Niemi M, et al. Among authors: neuvonen pj, neuvonen m. Clin Pharmacol Ther. 2000 Nov;68(5):495-500. doi: 10.1067/mcp.2000.111183. Clin Pharmacol Ther. 2000. PMID: 11103752 Clinical Trial.
Rifampin greatly reduces plasma simvastatin and simvastatin acid concentrations.
Kyrklund C, Backman JT, Kivistö KT, Neuvonen M, Laitila J, Neuvonen PJ. Kyrklund C, et al. Among authors: neuvonen pj, neuvonen m. Clin Pharmacol Ther. 2000 Dec;68(6):592-7. doi: 10.1067/mcp.2000.111414. Clin Pharmacol Ther. 2000. PMID: 11180018 Clinical Trial.
Effects of fluconazole and fluvoxamine on the pharmacokinetics and pharmacodynamics of glimepiride.
Niemi M, Backman JT, Neuvonen M, Laitila J, Neuvonen PJ, Kivistö KT. Niemi M, et al. Among authors: neuvonen pj, neuvonen m. Clin Pharmacol Ther. 2001 Apr;69(4):194-200. doi: 10.1067/mcp.2001.114229. Clin Pharmacol Ther. 2001. PMID: 11309547 Clinical Trial.
Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozil but not by bezafibrate.
Kyrklund C, Backman JT, Kivistö KT, Neuvonen M, Laitila J, Neuvonen PJ. Kyrklund C, et al. Among authors: neuvonen pj, neuvonen m. Clin Pharmacol Ther. 2001 May;69(5):340-5. doi: 10.1067/mcp.2001.115542. Clin Pharmacol Ther. 2001. PMID: 11372002 Clinical Trial.
Effects of rifampin on the pharmacokinetics and pharmacodynamics of glyburide and glipizide.
Niemi M, Backman JT, Neuvonen M, Neuvonen PJ, Kivistö KT. Niemi M, et al. Among authors: neuvonen pj, neuvonen m. Clin Pharmacol Ther. 2001 Jun;69(6):400-6. doi: 10.1067/mcp.2001.115822. Clin Pharmacol Ther. 2001. PMID: 11406737 Clinical Trial.
Plasma concentrations of inhaled budesonide and its effects on plasma cortisol are increased by the cytochrome P4503A4 inhibitor itraconazole.
Raaska K, Niemi M, Neuvonen M, Neuvonen PJ, Kivistö KT. Raaska K, et al. Among authors: neuvonen pj, neuvonen m. Clin Pharmacol Ther. 2002 Oct;72(4):362-9. doi: 10.1067/mcp.2002.127397. Clin Pharmacol Ther. 2002. PMID: 12386638 Clinical Trial.
Gemfibrozil inhibits CYP2C8-mediated cerivastatin metabolism in human liver microsomes.
Wang JS, Neuvonen M, Wen X, Backman JT, Neuvonen PJ. Wang JS, et al. Among authors: neuvonen pj, neuvonen m. Drug Metab Dispos. 2002 Dec;30(12):1352-6. doi: 10.1124/dmd.30.12.1352. Drug Metab Dispos. 2002. PMID: 12433802
Gemfibrozil greatly increases plasma concentrations of cerivastatin.
Backman JT, Kyrklund C, Neuvonen M, Neuvonen PJ. Backman JT, et al. Among authors: neuvonen pj, neuvonen m. Clin Pharmacol Ther. 2002 Dec;72(6):685-91. doi: 10.1067/mcp.2002.128469. Clin Pharmacol Ther. 2002. PMID: 12496749 Clinical Trial.
Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: potentially hazardous interaction between gemfibrozil and repaglinide.
Niemi M, Backman JT, Neuvonen M, Neuvonen PJ. Niemi M, et al. Among authors: neuvonen pj, neuvonen m. Diabetologia. 2003 Mar;46(3):347-51. doi: 10.1007/s00125-003-1034-7. Epub 2003 Feb 27. Diabetologia. 2003. PMID: 12687332 Clinical Trial.
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