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Effects of verapamil and diltiazem on the pharmacokinetics and pharmacodynamics of buspirone.

Lamberg TS, Kivistö KT, Neuvonen PJ. Lamberg TS, et al. Among authors: neuvonen pj. Clin Pharmacol Ther. 1998 Jun;63(6):640-5. doi: 10.1016/S0009-9236(98)90087-X. Clin Pharmacol Ther. 1998. PMID: 9663178 Clinical Trial.

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Itraconazole prevents terfenadine metabolism and increases risk of torsades de pointes ventricular tachycardia.

Pohjola-Sintonen S, Viitasalo M, Toivonen L, Neuvonen P. Pohjola-Sintonen S, et al. Eur J Clin Pharmacol. 1993;45(2):191-3. doi: 10.1007/BF00315505. Eur J Clin Pharmacol. 1993. PMID: 8223844

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Comparison of cyclophilin binding assay and radioimmunoassay in monitoring of blood cyclosporine.

Huupponen R, Hirvisalo EL, Neuvonen P. Huupponen R, et al. Ther Drug Monit. 1997 Aug;19(4):446-9. doi: 10.1097/00007691-199708000-00014. Ther Drug Monit. 1997. PMID: 9263387

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Response to "Interaction of Dasabuvir With Clopidogrel: Did Predictions by Physiologically Based Pharmacokinetics Modeling Pass the Test?".

Itkonen MK, Tornio A, Lapatto-Reiniluoto O, Neuvonen M, Neuvonen PJ, Niemi M, Backman JT. Itkonen MK, et al. Among authors: neuvonen pj. Clin Pharmacol Ther. 2019 Feb;105(2):322. doi: 10.1002/cpt.1195. Epub 2018 Sep 17. Clin Pharmacol Ther. 2019. PMID: 30226021 No abstract available.

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CYP3A4*22 Impairs the Elimination of Ticagrelor, But Has No Significant Effect on the Bioactivation of Clopidogrel or Prasugrel.

Holmberg MT, Tornio A, Paile-Hyvärinen M, Tarkiainen EK, Neuvonen M, Neuvonen PJ, Backman JT, Niemi M. Holmberg MT, et al. Among authors: neuvonen pj, neuvonen m. Clin Pharmacol Ther. 2019 Feb;105(2):448-457. doi: 10.1002/cpt.1177. Epub 2018 Aug 20. Clin Pharmacol Ther. 2019. PMID: 29998574

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Voriconazole more likely than posaconazole increases plasma exposure to sublingual buprenorphine causing a risk of a clinically important interaction.

Fihlman M, Hemmilä T, Hagelberg NM, Kuusniemi K, Backman JT, Laitila J, Laine K, Neuvonen PJ, Olkkola KT, Saari TI. Fihlman M, et al. Among authors: neuvonen pj. Eur J Clin Pharmacol. 2016 Nov;72(11):1363-1371. doi: 10.1007/s00228-016-2109-y. Epub 2016 Aug 10. Eur J Clin Pharmacol. 2016. PMID: 27510521 Clinical Trial.

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Effect of carboxylesterase 1 c.428G > A single nucleotide variation on the pharmacokinetics of quinapril and enalapril.

Tarkiainen EK, Tornio A, Holmberg MT, Launiainen T, Neuvonen PJ, Backman JT, Niemi M. Tarkiainen EK, et al. Among authors: neuvonen pj. Br J Clin Pharmacol. 2015 Nov;80(5):1131-8. doi: 10.1111/bcp.12667. Epub 2015 Jun 11. Br J Clin Pharmacol. 2015. PMID: 25919042 Free PMC article. Clinical Trial.

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Effects of terbinafine and itraconazole on the pharmacokinetics of orally administered tramadol.

Saarikoski T, Saari TI, Hagelberg NM, Backman JT, Neuvonen PJ, Scheinin M, Olkkola KT, Laine K. Saarikoski T, et al. Among authors: neuvonen pj. Eur J Clin Pharmacol. 2015 Mar;71(3):321-7. doi: 10.1007/s00228-014-1799-2. Epub 2015 Jan 6. Eur J Clin Pharmacol. 2015. PMID: 25560051 Clinical Trial.

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Rifampicin markedly decreases the exposure to oral and intravenous tramadol.

Saarikoski T, Saari TI, Hagelberg NM, Neuvonen M, Neuvonen PJ, Scheinin M, Olkkola KT, Laine K. Saarikoski T, et al. Among authors: neuvonen pj, neuvonen m. Eur J Clin Pharmacol. 2013 Jun;69(6):1293-301. doi: 10.1007/s00228-012-1460-x. Epub 2012 Dec 15. Eur J Clin Pharmacol. 2013. PMID: 23242004 Clinical Trial.

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Ticlopidine inhibits both O-demethylation and renal clearance of tramadol, increasing the exposure to it, but itraconazole has no marked effect on the ticlopidine-tramadol interaction.

Hagelberg NM, Saarikoski T, Saari TI, Neuvonen M, Neuvonen PJ, Turpeinen M, Scheinin M, Laine K, Olkkola KT. Hagelberg NM, et al. Among authors: neuvonen pj, neuvonen m. Eur J Clin Pharmacol. 2013 Apr;69(4):867-75. doi: 10.1007/s00228-012-1433-0. Epub 2012 Oct 26. Eur J Clin Pharmacol. 2013. PMID: 23099620 Clinical Trial.

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