New methodologies in the construction of dendritic materials.
Chem Soc Rev. 2009.
PMID: 19169453
Review.
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New methodologies in the construction of dendritic materials.
Chem Soc Rev. 2009 Feb;38(2):352-62. doi: 10.1039/b711745k. Epub 2008 Nov 25.
Chem Soc Rev. 2009.
PMID: 19169453
Review.
Due to their unique physical and chemical features, applications in areas such as targeted drug-delivery, macromolecular carriers, catalysis, sensors, light harvesting, surface engineering and biomimetic materials have been proposed. However, only a few dendritic …
Due to their unique physical and chemical features, applications in areas such as targeted drug-delivery, macromolecular carriers, catalysis …
Identification of key biomarkers and immune infiltration in the synovial tissue of osteoarthritis by bioinformatics analysis.
PeerJ. 2020 Jan 17;8:e8390. doi: 10.7717/peerj.8390. eCollection 2020.
PeerJ. 2020.
PMID: 31988808
Free PMC article.
OBJECTIVE: This study was designed to identify key biomarkers and immune infiltration in the synovial tissue of osteoarthritis by bioinformatics analysis. MATERIALS AND METHODS: The gene expression profiles of GSE12021, GSE55235 and GSE55457 were downloaded from the …
OBJECTIVE: This study was designed to identify key biomarkers and immune infiltration in the synovial tissue of osteoarthritis by bioinforma …
Dendrimer disassembly as a new paradigm for the application of dendritic structures.
Mol Pharm. 2005 Jul-Aug;2(4):253-63. doi: 10.1021/mp050047x.
Mol Pharm. 2005.
PMID: 16053328
Review.
This is a powerful construct, in that dendrimers and dendritic structures can be made up of a wide variety of subunits, compatibilized with many different environments, and incorporated into countless systems. We anticipate that dendritic materials wit …
This is a powerful construct, in that dendrimers and dendritic structures can be made up of a wide variety of subunits, compat …
Biomaterial-Based Activation and Expansion of Tumor-Specific T Cells.
Front Immunol. 2019 May 3;10:931. doi: 10.3389/fimmu.2019.00931. eCollection 2019.
Front Immunol. 2019.
PMID: 31130945
Free PMC article.
Review.
Traditional tumor vaccination approaches mostly focus on activating dendritic cells (DCs) by providing them with a source of tumor antigens and/or adjuvants, which in turn activate tumor-reactive T cells. Novel biomaterial-based cancer immunotherapeutic strategies focus on …
Traditional tumor vaccination approaches mostly focus on activating dendritic cells (DCs) by providing them with a source of tumor an …
Hypoxic Three-Dimensional Cellular Network Construction Replicates Ex Vivo the Phenotype of Primary Human Osteocytes.
Tissue Eng Part A. 2018 Mar;24(5-6):458-468. doi: 10.1089/ten.TEA.2017.0103. Epub 2017 Aug 2.
Tissue Eng Part A. 2018.
PMID: 28594289
Free PMC article.
Osteocytes are deeply embedded in the mineralized matrix of bone and are nonproliferative, making them a challenge to isolate and maintain using traditional in vitro culture methods without sacrificing their inimitable phenotype. We studied the synergistic effects of two m …
Osteocytes are deeply embedded in the mineralized matrix of bone and are nonproliferative, making them a challenge to isolate and maintain u …
Engineering DNA-based functional materials.
Chem Soc Rev. 2011 Dec;40(12):5730-44. doi: 10.1039/c1cs15162b. Epub 2011 Aug 19.
Chem Soc Rev. 2011.
PMID: 21858293
Review.
In this tutorial review, we focus on two aspects of using DNA as a polymeric material: (1) the engineering methods, and (2) the potential real-world applications. More specifically, various strategies for constructing DNA-based building blocks a …
In this tutorial review, we focus on two aspects of using DNA as a polymeric material: (1) the engineering methods, and …
Synthesis and characterization of nanoscale dendritic RGD clusters for potential applications in tissue engineering and drug delivery.
Int J Nanomedicine. 2007;2(1):89-99. doi: 10.2147/nano.2007.2.1.89.
Int J Nanomedicine. 2007.
PMID: 17722516
Free PMC article.
Dendrimers have a unique, highly branched, nearly spherical and symmetrical structure with low polydispersity, nanoscale size, and high functionality. Therefore, dendrimers are a class of ideal scaffold for construction of nanoscale dendritic RGD clusters in which R …
Dendrimers have a unique, highly branched, nearly spherical and symmetrical structure with low polydispersity, nanoscale size, and high func …
Gene-modified tissue-engineered skin: the next generation of skin substitutes.
Adv Biochem Eng Biotechnol. 2007;103:241-74. doi: 10.1007/10_023.
Adv Biochem Eng Biotechnol. 2007.
PMID: 17195466
Review.
Tissue engineering combines the principles of cell biology, engineering and materials science to develop three-dimensional tissues to replace or restore tissue function. Tissue engineered skin is one of most advanced tissue constructs, yet it lacks several important …
Tissue engineering combines the principles of cell biology, engineering and materials science to develop three-dimensional tissues to …
Towards a hexa-branched [7]rotaxane from a [3]rotaxane via a [2+2+2] alkyne cyclotrimerization process.
Chem Commun (Camb). 2019 Mar 19;55(24):3525-3528. doi: 10.1039/c9cc00363k.
Chem Commun (Camb). 2019.
PMID: 30839035
A facile synthesis methodology to obtain a crown ether-based hexa-branched [7]rotaxane, has been achieved by using Co-catalyzed [2+2+2] alkyne cyclotrimerization from a [3]rotaxane. The [2+2+2] alkyne cyclotrimerization process, which requires only 10 mol% of Co2(CO)8 as a …
A facile synthesis methodology to obtain a crown ether-based hexa-branched [7]rotaxane, has been achieved by using Co-catalyzed [2+2+ …
Novel gene therapy viral vector using non-oncogenic lymphotropic herpesvirus.
PLoS One. 2013;8(2):e56027. doi: 10.1371/journal.pone.0056027. Epub 2013 Feb 11.
PLoS One. 2013.
PMID: 23409116
Free PMC article.
In addition, retroviral vectors carry risks associated with the oncogenicity of the native virus and the potential for introducing malignancy in recipients due to genetic carryover from immortalized cells used during vector production. To address these issues, we have established …
In addition, retroviral vectors carry risks associated with the oncogenicity of the native virus and the potential for introducing malignanc …
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