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Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding.
Newberry RW, Arhar T, Costello J, Hartoularos GC, Maxwell AM, Naing ZZC, Pittman M, Reddy NR, Schwarz DMC, Wassarman DR, Wu TS, Barrero D, Caggiano C, Catching A, Cavazos TB, Estes LS, Faust B, Fink EA, Goldman MA, Gomez YK, Gordon MG, Gunsalus LM, Hoppe N, Jaime-Garza M, Johnson MC, Jones MG, Kung AF, Lopez KE, Lumpe J, Martyn C, McCarthy EE, Miller-Vedam LE, Navarro EJ, Palar A, Pellegrino J, Saylor W, Stephens CA, Strickland J, Torosyan H, Wankowicz SA, Wong DR, Wong G, Redding S, Chow ED, DeGrado WF, Kampmann M. Newberry RW, et al. ACS Chem Biol. 2020 Aug 21;15(8):2137-2153. doi: 10.1021/acschembio.0c00339. Epub 2020 Aug 12. ACS Chem Biol. 2020. PMID: 32786289 Free PMC article.
The n→π* Interaction.
Newberry RW, Raines RT. Newberry RW, et al. Acc Chem Res. 2017 Aug 15;50(8):1838-1846. doi: 10.1021/acs.accounts.7b00121. Epub 2017 Jul 23. Acc Chem Res. 2017. PMID: 28735540 Free PMC article.
Interplay of hydrogen bonds and n→π* interactions in proteins.
Bartlett GJ, Newberry RW, VanVeller B, Raines RT, Woolfson DN. Bartlett GJ, et al. Among authors: newberry rw. J Am Chem Soc. 2013 Dec 11;135(49):18682-8. doi: 10.1021/ja4106122. Epub 2013 Dec 3. J Am Chem Soc. 2013. PMID: 24256417 Free PMC article.
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