Newgard CB - Search Results

1

The coactivator SRC-1 is an essential coordinator of hepatic glucose production.

Louet JF, Chopra AR, Sagen JV, An J, York B, Tannour-Louet M, Saha PK, Stevens RD, Wenner BR, Ilkayeva OR, Bain JR, Zhou S, DeMayo F, Xu J, Newgard CB, O'Malley BW. Louet JF, et al. Among authors: newgard cb. Cell Metab. 2010 Dec 1;12(6):606-18. doi: 10.1016/j.cmet.2010.11.009. Cell Metab. 2010. PMID: 21109193 Free PMC article.

2

Overexpression of the P46 (T1) translocase component of the glucose-6-phosphatase complex in hepatocytes impairs glycogen accumulation via hydrolysis of glucose 1-phosphate.

An J, Li Y, van De Werve G, Newgard CB. An J, et al. Among authors: newgard cb. J Biol Chem. 2001 Apr 6;276(14):10722-9. doi: 10.1074/jbc.M009525200. Epub 2001 Jan 8. J Biol Chem. 2001. PMID: 11148207 Free article.

3

Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance.

An J, Muoio DM, Shiota M, Fujimoto Y, Cline GW, Shulman GI, Koves TR, Stevens R, Millington D, Newgard CB. An J, et al. Among authors: newgard cb. Nat Med. 2004 Mar;10(3):268-74. doi: 10.1038/nm995. Epub 2004 Feb 8. Nat Med. 2004. PMID: 14770177

4

Hyperlipidemic effects of dietary saturated fats mediated through PGC-1beta coactivation of SREBP.

Lin J, Yang R, Tarr PT, Wu PH, Handschin C, Li S, Yang W, Pei L, Uldry M, Tontonoz P, Newgard CB, Spiegelman BM. Lin J, et al. Among authors: newgard cb. Cell. 2005 Jan 28;120(2):261-73. doi: 10.1016/j.cell.2004.11.043. Cell. 2005. PMID: 15680331 Free article.

5

Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion.

Jensen MV, Joseph JW, Ilkayeva O, Burgess S, Lu D, Ronnebaum SM, Odegaard M, Becker TC, Sherry AD, Newgard CB. Jensen MV, et al. Among authors: newgard cb. J Biol Chem. 2006 Aug 4;281(31):22342-22351. doi: 10.1074/jbc.M604350200. Epub 2006 Jun 1. J Biol Chem. 2006. PMID: 16740637 Free article.

6

A pyruvate cycling pathway involving cytosolic NADP-dependent isocitrate dehydrogenase regulates glucose-stimulated insulin secretion.

Ronnebaum SM, Ilkayeva O, Burgess SC, Joseph JW, Lu D, Stevens RD, Becker TC, Sherry AD, Newgard CB, Jensen MV. Ronnebaum SM, et al. Among authors: newgard cb. J Biol Chem. 2006 Oct 13;281(41):30593-602. doi: 10.1074/jbc.M511908200. Epub 2006 Aug 15. J Biol Chem. 2006. PMID: 16912049 Free article.

7

Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis.

Zhang YM, Chohnan S, Virga KG, Stevens RD, Ilkayeva OR, Wenner BR, Bain JR, Newgard CB, Lee RE, Rock CO, Jackowski S. Zhang YM, et al. Among authors: newgard cb. Chem Biol. 2007 Mar;14(3):291-302. doi: 10.1016/j.chembiol.2007.01.013. Chem Biol. 2007. PMID: 17379144 Free PMC article.

8

Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver.

Monetti M, Levin MC, Watt MJ, Sajan MP, Marmor S, Hubbard BK, Stevens RD, Bain JR, Newgard CB, Farese RV Sr, Hevener AL, Farese RV Jr. Monetti M, et al. Among authors: newgard cb. Cell Metab. 2007 Jul;6(1):69-78. doi: 10.1016/j.cmet.2007.05.005. Cell Metab. 2007. PMID: 17618857 Free article.

9

Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle.

Levin MC, Monetti M, Watt MJ, Sajan MP, Stevens RD, Bain JR, Newgard CB, Farese RV Sr, Farese RV Jr. Levin MC, et al. Among authors: newgard cb. Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1772-81. doi: 10.1152/ajpendo.00158.2007. Epub 2007 Oct 16. Am J Physiol Endocrinol Metab. 2007. PMID: 17940217 Free article.

10

Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance.

Koves TR, Ussher JR, Noland RC, Slentz D, Mosedale M, Ilkayeva O, Bain J, Stevens R, Dyck JR, Newgard CB, Lopaschuk GD, Muoio DM. Koves TR, et al. Among authors: newgard cb. Cell Metab. 2008 Jan;7(1):45-56. doi: 10.1016/j.cmet.2007.10.013. Cell Metab. 2008. PMID: 18177724 Free article.

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