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[A new Achilles' heel in the tuberculosis bacillus].
Gutierrez C, Neyrolles O. Gutierrez C, et al. Among authors: neyrolles o. Med Sci (Paris). 2019 Oct;35(10):746-748. doi: 10.1051/medsci/2019145. Epub 2019 Oct 18. Med Sci (Paris). 2019. PMID: 31625895 French. No abstract available.
The synthesis and in vitro biological evaluation of novel fluorinated tetrahydrobenzo[j]phenanthridine-7,12-diones against Mycobacterium tuberculosis.
Cappoen D, Torfs E, Meiresonne T, Claes P, Semina E, Holvoet F, de Macedo MB, Cools F, Piller T, Matheeussen A, Van Calster K, Caljon G, Delputte P, Maes L, Neyrolles O, De Kimpe N, Mangelinckx S, Cos P. Cappoen D, et al. Among authors: neyrolles o. Eur J Med Chem. 2019 Nov 1;181:111549. doi: 10.1016/j.ejmech.2019.07.052. Epub 2019 Jul 19. Eur J Med Chem. 2019. PMID: 31376569
DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells.
Tailleux L, Schwartz O, Herrmann JL, Pivert E, Jackson M, Amara A, Legres L, Dreher D, Nicod LP, Gluckman JC, Lagrange PH, Gicquel B, Neyrolles O. Tailleux L, et al. Among authors: neyrolles o. J Exp Med. 2003 Jan 6;197(1):121-7. doi: 10.1084/jem.20021468. J Exp Med. 2003. PMID: 12515819 Free PMC article.
Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity.
Pitarque S, Herrmann JL, Duteyrat JL, Jackson M, Stewart GR, Lecointe F, Payre B, Schwartz O, Young DB, Marchal G, Lagrange PH, Puzo G, Gicquel B, Nigou J, Neyrolles O. Pitarque S, et al. Among authors: neyrolles o. Biochem J. 2005 Dec 15;392(Pt 3):615-24. doi: 10.1042/BJ20050709. Biochem J. 2005. PMID: 16092920 Free PMC article.
DC-SIGN induction in alveolar macrophages defines privileged target host cells for mycobacteria in patients with tuberculosis.
Tailleux L, Pham-Thi N, Bergeron-Lafaurie A, Herrmann JL, Charles P, Schwartz O, Scheinmann P, Lagrange PH, de Blic J, Tazi A, Gicquel B, Neyrolles O. Tailleux L, et al. Among authors: neyrolles o. PLoS Med. 2005 Dec;2(12):e381. doi: 10.1371/journal.pmed.0020381. Epub 2005 Nov 15. PLoS Med. 2005. PMID: 16279841 Free PMC article.
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