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Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients.
Funnell SGP, Dowling WE, Muñoz-Fontela C, Gsell PS, Ingber DE, Hamilton GA, Delang L, Rocha-Pereira J, Kaptein S, Dallmeier KH, Neyts J, Rosenke K, de Wit E, Feldmann H, Maisonnasse P, Le Grand R, Frieman MB, Coleman CM. Funnell SGP, et al. Among authors: neyts j. Nat Commun. 2020 Aug 26;11(1):4253. doi: 10.1038/s41467-020-17907-w. Nat Commun. 2020. PMID: 32848158 Free PMC article.
Debio 025, a cyclophilin binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically targeted antiviral therapy for HCV (STAT-C) inhibitors.
Coelmont L, Kaptein S, Paeshuyse J, Vliegen I, Dumont JM, Vuagniaux G, Neyts J. Coelmont L, et al. Among authors: neyts j. Antimicrob Agents Chemother. 2009 Mar;53(3):967-76. doi: 10.1128/AAC.00939-08. Epub 2008 Dec 22. Antimicrob Agents Chemother. 2009. PMID: 19104013 Free PMC article.
662 results